نتایج جستجو برای: neutrophil gelatinase associated lipocalin and interleukin 18
تعداد نتایج: 17073051 فیلتر نتایج به سال:
Introduction. The effect of various minimally invasive treatment for kidney stones on renal function has not been sufficiently studied. To assess the specificity, severity, and prognostic significance injury urolithiasis its treatment, it is necessary to search «biomarkers injury». concentration serum urea creatinine used in routine clinical practice, glomerular filtration rate change later sta...
AIMS Neutrophil gelatinase-associated lipocalin (NGAL or lipocalin-2) is a glycoprotein with bacteriostatic properties. Growing evidence suggests that NGAL may also be involved in cell survival, inflammation, and matrix degradation. We therefore aimed to investigate the role of NGAL in heart failure (HF). METHODS AND RESULTS Our main findings were (i) patients with acute post-myocardial infar...
Compelling evidence has demonstrated that arsenic (As) exposure is associated with kidney injuries. Given inflammatory responses and immune imbalances are the root causes of several diseases, this study investigated potential mechanisms underlying NLRP3 inflammasome activation in As-induced injury. A rat model sub-chronic As was established via oral administration NaAsO2. The results revealed u...
BACKGROUND Neutrophil gelatinase-associated lipocalin (NGAL) is an early marker of acute kidney injury (AKI). METHODS AND RESULTS Urine NGAL and serum NGAL (sNGAL) were assessed at 2, 6, 24, and 48 hours after contrast media (CM) exposure in 458 high-risk patients (development set). Optimal thresholds in predicting contrast-induced AKI (serum creatinine [sCr] increase ≥0.3 mg/dL at 48 hours a...
AbstractObjective Neutrophils induce inflammation through the exocytosis of cytotoxic granule proteins. Recently, neutrophils have been reported to be an independent parameter associated with unfavorable outcomes after subarachnoid hemorrhage (SAH). However, mechanism by which accumulate within CSF SAH remains undetermined. Methods Concentrations C5a, epithelial neutr...
Oxidative stress and inflammation are part and parcel of cisplatin-induced nephrotoxicity. The purpose of this work is to study the role of soy isoflavone constituent, daidzein, in cisplatin-induced renal damage. Cisplatin-induced nephrotoxicity was evident by the histological damage in proximal tubular cells and by the increase in serum neutrophil gelatinase-associated lipocalin (NGAL), blood ...
Delayed graft function (DGF) due to tubule cell injury frequently complicates deceased donor kidney transplants. We tested whether urinary neutrophil gelatinase-associated lipocalin (NGAL) and interleukin-18 (IL-18) represent early biomarkers for DGF (defined as dialysis requirement within the first week after transplantation). Urine samples collected on day 0 from recipients of living donor ki...
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