Hubs integrate and distribute information in powerful ways due to the number and positioning of their contacts in a network. Several resting-state functional connectivity MRI reports have implicated regions of the default mode system as brain hubs; we demonstrate that previous degree-based approaches to hub identification may have identified portions of large brain systems rather than critical ...

Although competing endogenous RNAs (ceRNAs) have been implicated in many solid tumors, their roles in breast cancer subtypes are not well understood. We therefore generated a ceRNA network for each subtype based on the significance of both, positive co-expression and the shared miRNAs, in the corresponding subtype miRNA dys-regulatory network, which was constructed based on negative regulations...

Detecting regional spatial structures based on spatial interactions is crucial in applications ranging from urban planning to traffic control. In the big data era, various movement trajectories are available for studying spatial structures. This research uses large scale Shanghai taxi trip data extracted from GPS-enabled taxi trajectories to reveal traffic flow patterns and urban structure of t...

Hierarchical multimodal hub location problem is a cost-minimizing hub covering problem where two types of hubs and hub links, accounting for ground and air transportation, are to be established, while ensuring time-definite deliveries. We propose a mixed-integer programming formulation and perform a comprehensive sensitivity analysis on the Turkish network. We show that the locations of airport...

The hub location problem with single assignment is the problem of locating hubs and assigning the terminal nodes to hubs in order to minimize the cost of hub installation and the cost of routing the traffic in the network. There may also be capacity restrictions on the amount of traffic that can transit by hubs. The aim of this paper is to investigate polyhedral properties of these problems and...

In previous Extension articles, we discussed traditional Ethernet and its dependency on repeater sets to expand the length of these networks. As Ethernet evolved to incorporate twisted-pair cabling and star topology, a repeating hub was necessary in order to connect the various link segments together. With the introduction of switching hubs as a replacement for repeating hubs, network performan...

Recent developments in network theory have allowed for the study of the structure and function of the human brain in terms of a network of interconnected components. Among the many nodes that form a network, some play a crucial role and are said to be central within the network structure. Central nodes may be identified via centrality metrics, with degree, betweenness, and eigenvector centralit...

Ranch industry has grown bigger. In Australia, ranches have very large number of livestock commodities: cattle, lambs, and muttons. To manage such a very large scale commodities, they need to install sensor network with MapReduce of Hadoop; since the sensor network generates a huge amount of data. The ranch is divided into several patterned regions and a lot of hubs are installed in there for r...