Previous studies have demonstrated that the epithelium of the respiratory portion of rat nasal mucosa is amply supplied by nerve fibers with immunoreactivities for calcitonin gene-related peptide (CGRP) and substance P (SP), these fibers most likely acting as sensory mediators in the mucosa. The present study demonstrates that some intraepithelial fibers contain a VIP-immunoreactivity whose occ...

The distribution of acetylcholinesterase in the canine kidney was studied by the histochemical method of Karnovsky and Roots and compared to the distribution of adrenergic fibers studied with the fluorescence histochemical method of Falck and Hillarp. Specific inhibitors of nonspecific cholinesterase and acetylcholinesterase were used to differentiate between the two enzymes. In the hilus, acet...

A dense plexus of CGRP-immunoreactive nerve fibers was found subjacent to and within the epithelium of the excretory ducts of the parotid, submandibular and sublingual glands in the rat, in close proximity to the opening into the oral cavity. The immunoreactive nerve fibers disappeared after a neonatal administration of capsaicin. In immuno-electron microscopy, the immunoreactive nerve fibers w...

The indirect immunofluorescence technique with antisera either to avian pancreatic polypeptide or to bovine pancreatic polypeptide stains nerve fibers in the guinea pig eye. In all regions of the uvea, immunoreactive fibers are present around large blood vessels; an association of immunoreactive nerve fibers to melanocytes is seen. Immunoreactive nerves are found throughout the choroid, includi...

Discharge rates for populations of single auditory nerve fibers in response to 1.5 kHz tone bursts were measured in anesthetized cats. Separate plots of average rate vs. best frequency (rate-place profiles) were made for high, medium and low spontaneous rate (SR) auditory nerve fibers. At the lowest sound levels studied (34 dB SPL), all three SR groups show a peak in the rate-place profile cent...

background: endometriosis is a disease that is hard to diagnose without the gold standard method, laparoscopy. an easier diagnostic method is needed. objective: the aim of the study is to determine whether the number of macrophage cells in the endometrium and/or the detection of nerve fibers can be used in the diagnosis of endometriosis. materials and methods: endometrial sampling was done to 3...

Anatomical evidence of the presence of efferent fibers in the visual systems of vertebrates is fragmentary and to a large extent controversial. The efferent nerve supply to the sensory receptors including the visual system, however, is important in the physiology of regulation of the sensitivity of the receptors. The presence of efferent fibers in the retina was first suggested by R a m ó n y C...

Superior oblique muscle/trochlear nerve pairs from goldfish of various ages (1-5 years) have been examined light and electron microscopically. The muscle grows by enlargement (longitudinally and transversely) of individual fibers, and by addition of new ones at the rate of about 250/year. The nerve grows by enlargement of fibers, but few and perhaps no new axons are added. The somata enlarge, a...

Diabetic polyneuropathy is a specific form of peripheral nerve disorder, in which distal nerve axons degenerate insidiously under hyperglycemia of diabetes mellitus. Although all types of peripheral nerve fibers are involved, it is usually sensory dominant with eventual involvement of autonomic and motor nerve fibers. Its manifestation ranges from subclinical changes in nerve conduction to pain...

Poly(glycolic acid) (PGA) fibers are a good candidate material for nerve cell scaffolds, which is applicable to the treatment of peripheral nerve injuries. Polylysine is widely used as a coating material for cell substrates to promote nerve cell adhesion. In this study, linear and dendrigraft polylysines were used to coat PGA fibers. The association of large dendrigraft polylysines with PGA fib...