نتایج جستجو برای: nerve degeneration

تعداد نتایج: 211971  

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2016
Martha R C Bhattacharya Stefanie Geisler Sara K Pittman Ryan A Doan Conrad C Weihl Jeffrey Milbrandt Aaron DiAntonio

UNLABELLED Complex nervous systems achieve proper connectivity during development and must maintain these connections throughout life. The processes of axon and synaptic maintenance and axon degeneration after injury are jointly controlled by a number of proteins within neurons, including ubiquitin ligases and mitogen activated protein kinases. However, our understanding of these molecular casc...

Journal: :Journal of neuropathology and experimental neurology 2009
Yasushi Kitaoka Yasuhiro Hayashi Toshio Kumai Hiroyuki Takeda Yasunari Munemasa Hiromi Fujino Yuka Kitaoka Satoki Ueno Alfredo A Sadun Tim T Lam

Axonal degeneration often leads to the death of neuronal cell bodies. Previous studies have demonstrated the crucial role of nicotinamide adenine dinucleotide (NAD) biosynthesis in axonal protection of motor neurons, but the role of nicotinamide mononucleotide adenylyltransferase 1 and NAD in optic nerve degeneration is unclear. Intravitreal injection of tumor necrosis factor (TNF) induces opti...

Journal: :AJNR. American journal of neuroradiology 1989
D S Titelbaum J L Frazier R I Grossman P M Joseph L T Yu E A Kassab W F Hickey D LaRossa M J Brown

To investigate the role of MR imaging in wallerian degeneration, a series of animal models of increasingly complex peripheral nerve injury were studied by in vivo MR. Proximal tibial nerves in brown Norway rats were either crushed, transected (neurotomy), or transected and grafted with Lewis rat (allograft) or brown Norway (isograft) donor nerves. The nerves distal to the site of injury were im...

2018
Ying-hua Zhao Shi-jian Zhang Zi-hui Yang Xiao-chang Liu De-lin Lei Jing Li Lei Wang

Distraction osteogenesis is an important technique for the treatment of maxillofacial abnormities and defects. However, distraction osteogenesis may cause the injury of the inferior alveolar nerve. The relationship between distraction rate and nerve degeneration-regeneration shift remains poorly understood. In this study, 24 rabbits were randomly divided into four groups. To establish the rabbi...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2013
Bibhudatta Mishra Ross Carson Richard I Hume Catherine A Collins

Axons degenerate after injury and in neuropathies and disease via a self-destruction program whose mechanism is poorly understood. Axons that have lost connection to their cell bodies have altered electrical and synaptic activities, but whether such changes play a role in the axonal degeneration process is not clear. We have used a Drosophila model to study the Wallerian degeneration of motoneu...

2017
M Charles Liberman

The classic view of sensorineural hearing loss has been that the primary damage targets are hair cells and that auditory nerve loss is typically secondary to hair cell degeneration. Recent work has challenged that view. In noise-induced hearing loss, exposures causing only reversible threshold shifts (and no hair cell loss) nevertheless cause permanent loss of >50% of the synaptic connections b...

Mehrnoosh Hashemi, Zahra Ghorbanifar,

Stem cells are undifferentiated cells that have the ability to convert to different types of cells and after dividing, they can produce their own cells or other cells. Axons of the retinal ganglion cells, from the optic nerve. These cells lose the ability to regenerate themselves before birth. Optic nerve degeneration can result from various causes including increased intraocular pressure, comp...

Journal: :Orphanet Journal of Rare Diseases 2018

Journal: :Journal of Neurogastroenterology and Motility 2019

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید