نتایج جستجو برای: nerve conduit

تعداد نتایج: 170300  

Journal: :Neuroscience 2011
A J Reid M Sun M Wiberg S Downes G Terenghi P J Kingham

Novel approaches are required in the clinical management of peripheral nerve injuries because current surgical techniques result in deficient sensory recovery. Microsurgery alone fails to address extensive cell death in the dorsal root ganglia (DRG), in addition to poor axonal regeneration. Incorporation of cultured cells into nerve conduits may offer a novel approach in which to combine nerve ...

2013
Fatemeh Mottaghitalab Mehdi Farokhi Arash Zaminy Mehrdad Kokabi Masoud Soleimani Fereshteh Mirahmadi Mohammad Ali Shokrgozar Majid Sadeghizadeh

As a contribution to the functionality of nerve guide conduits (NGCs) in nerve tissue engineering, here we report a conduit processing technique through introduction and evaluation of topographical, physical and chemical cues. Porous structure of NGCs based on freeze-dried silk/single walled carbon nanotubes (SF/SWNTs) has shown a uniform chemical and physical structure with suitable electrical...

2014
Tetsuro Tamaki

Long gap peripheral nerve injuries usually reulting in life-changing problems for patients. Skeletal muscle derived-multipotent stem cells (Sk-MSCs) can differentiate into Schwann and perineurial/endoneurial cells, vascular relating pericytes, and endothelial and smooth muscle cells in the damaged peripheral nerve niche. Application of the Sk-MSCs in the bridging conduit for repairing long nerv...

2014
Julia T. Oliveira Ruben Ernesto Bittencourt-Navarrete Fernanda M. de Almeida Chiara Tonda-Turo Ana Maria B. Martinez João G. Franca

We studied the morphology and the cortical representation of the median nerve (MN), 10 weeks after a transection immediately followed by treatment with tubulization using a polycaprolactone (PCL) conduit with or without bone marrow-derived mesenchymal stem cell (MSC) transplant. In order to characterize the cutaneous representation of MN inputs in primary somatosensory cortex (S1), electrophysi...

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