The purpose of this study was to compare histologic subtype and growth pattern, including invasion and intraductal spread to branch ducts, in main duct-type intraductal papillary-mucinous carcinoma (IPMC) by histopathology and immunohistochemistry. Five surgically resected samples of main duct-type IPMC from five patients, were studied. Main lesions, invasive components, and adjacent secondary ...

Glioblastoma multiforme (GBM) is an aggressively invasive brain neoplasm with poor patient prognosis. We have previously shown that the bioactive lipid sphingosine-1-phosphate (S1P) stimulates in vitro invasiveness of GBM cells and that high expression levels of the enzyme that forms S1P, sphingosine kinase-1 (SphK1), correlate with shorter survival time of GBM patients. We also recently showed...

Abstract Nowadays, as accepted as the era of information or digital, time has changed and has invited all people to a new world in which everybody must define himself. Avoiding from getting benefit from this human progress is useless; Rather, we must know this great technology best and adapt ourselves with its consequences. In fact, in many countries and among many nations there had been peopl...

Abstract Subset of patients with H3G34 gliomas may present extra-CNS metastasis further complicating both diagnosis and treatment. We describe a case 19-year-old female presenting initially focal motor seizure in right leg along pain. MRI the showed an ill-defined distal femur expansile osteolytic lesion central fluid signal, thick rim enhancement, endosteal scalloping, cortical invasion, smoot...

Abstract Bladder cancer is the most common neoplasm of urinary system, and urothelial carcinoma histological type bladder (approximately 90%), represents invasion basement membrane or lamina propria by cells. Most people with have hematuria doctor should be consulted as soon possible a specialist scheduled to examine camera - cystoscopy. The present study retrospective that includes 174 patient...

Neuroblastoma is the most frequently diagnosed cancer during first year of life. This neoplasm originates from neural crest cells derived sympathetic nervous system, adrenal medulla, or paraspinal ganglia. The clinical presentation can vary an asymptomatic mass to symptoms resulting local invasion and/or spread distant disease spread. natural history neuroblastoma highly variable, ranging relat...

Intraductal papillary neoplasm of the bile duct (IPNB) represents biliary papillary tumors mainly growing and is considered to be of relatively low-grade malignancy. Here we report a case of IPNB in whom the poorly differentiated component deeply infiltrated the bile duct wall. A 77-year-old male had an invasive carcinoma of the bile duct 3 cm in size. He underwent right hemihepatectomy with co...

A 74-year-old man was referred to our hospital for a mass in the pancreatic head found during screening chest computed tomography. Contrast computed tomography showed a 5-cm multicystic mass with an irregular border containing a solid component showing contrast enhancement. Caudal to this mass, a 5-cm solid mass of fat density with a nodular soft-tissue component was found. Cytology of the aspi...

results: among 11 patients who underwent surgery consisted of eight males and three females. their metastasis originated from testis tumors (n = 5), renal cell carcinoma (rcc; n = 4), bladder tumor (n = 1), and prostate cancer (n = 1). their mean age was 41.27 years (range, 21-67). the mean age of the patients with rcc and testis tumor at the time of diagnosing metastasis was 54 and 24.8 years,...