Successful completion of the Plasmodium lifecycle in the mosquito vector is critical for malaria transmission. It has been documented that the fate of Plasmodium in the mosquito ultimately depends on a fine interplay of molecular mosquito factors that act as parasite agonists and antagonists. Here we investigate whether the cellular responses of the invaded midgut epithelium can also determine ...

BACKGROUND AND OBJECTIVE Primary ciliary dyskinesia (PCD) is a rare inherited disease affecting motile cilia lining the respiratory tract. Despite neonatal respiratory distress as an early feature, diagnosis is typically delayed until late childhood. Our objective was to identify characteristics that differentiate PCD from common causes of term neonatal respiratory distress. METHODS This was ...

Laser-assisted flow-visualization experiments and tracer gas concentration tests were conducted for the wall-mounted and jet-isolated range hoods to examine the physical mechanisms and relative magnitudes of hood spillages. The effects of a mannequin standing in front of the test rig and walk-by motions (which are situations always encountered in kitchens) were emphasized. The results showed th...

For more than 100 years, three principles have guided the treatment of neonatal asphyxia: maintain body heat, free air passages of obstructions, and stimulate respiration by supplying air to the lungs for oxygenation of the blood. This article addresses the question of which gas, air or 100% oxygen, is best supplied to the lungs to stimulate respiration. Evidence-based studies are presented and...

In the neonatal period, the clinical use of oxygen should be taken into consideration for its beneficial and toxicity effects. Oxygen toxicity is due to the development of reactive oxygen species (ROS) such as OH• that is one of the strongest oxidants in nature. Of note, generation of ROS is a normal occurrence in human and it is involved in a myriad of physiological reactions. Anyway an imbala...

Although the incidence of pneumoconiosis has been decreasing in Japan, welders’ health hazards due to welding fume inhalation are still serious, because effective engineering methods for controlling fumes are technically difficult to implement in many welding shops. In the 6th notification of general prevention of dust hazards issued by the Japanese Ministry of Health, Labor and Welfare (2003–2...

background ureaplasma urealyticum (u. urealyticum) and mycoplasma hominis (m. hominis) are two important pathogens in neonatal respiratory tract infections. as low gestational age and birth weight increase the colonization rate with these pathogens, and they are also risk factors of chronic lung disease (cld), it is difficult to establish a statistically significant relation between these two f...