PURPOSE OF REVIEW The overwhelming majority of the world's annual 4 million neonatal deaths occur in developing countries. This review therefore briefly addresses the burden, aetiology, prevention and management of serious neonatal bacterial infections in low-income settings. RECENT FINDINGS Bacterial infection is the biggest cause of neonatal admissions to hospitals, and probably the biggest...

hook worm (necator americanus) is one of the major pathogenic parasites in the north of iran. neonatal hamsters 1-3 days old showed a high degree of susceptibility to necator americanus infection and the parasite reached to sexually mature stages in six weeks following skin exposure. this method could be used for production of egg, larvae and adult worms. in this study neonatal hamsters were in...

Background: Coronavirus disease 2019 (COVID-19) infection is continuing its spread across the world with nearly 13 million people involvement by 11 July 2020. It mainly causes respiratory infection and affects different people in different ways. The COVID-19 infection involves many pregnant women worldwide, and maternal-fetal transmission of viral diseases is a major concern about this virus. H...

BACKGROUND Around 1.5 million annual neonatal deaths occur in the first week of life, and infections represent one of the major causes in developing countries. Neonatal sepsis is often strictly connected to infection of the maternal genital tract during labour. METHODS The association between signs suggestive of puerperal infection and early neonatal mortality (<7 days of life) was performed ...

PATIENT Male, 0 FINAL DIAGNOSIS: Purpura fulminans Symptoms: Fever • letargy MEDICATION - Clinical Procedure: - Specialty: Pediatrics and Neonatology. OBJECTIVE Rare disease. BACKGROUND Neonatal purpura fulminans (PF) is a rare but frequently fatal disorder associated with high morbidity and mortality. It may be congenital, as a result of protein C and S deficiency, or acquired due to sev...

Infectious Diseases, National Institutes of Health (NIH). The NIH has patents, pending patent applications, and a license for rhesus and rhesus-human rotavirus reassortant vaccines; patents, pending patent applications, and licenses for human-bovine (UK) rotavirus reassortant vaccines; a patent for cold-adapted human rotavirus vaccines; and a pending patent application for human-porcine rotavir...

While antibody responses to neurovirulent pathogens are critical for clearance, the extent to which antibodies access the nervous system to ameliorate infection is poorly understood. In this study on herpes simplex virus 1 (HSV-1), we demonstrate that HSV-specific antibodies are present during HSV-1 latency in the nervous systems of both mice and humans. We show that antibody-secreting cells en...