BACKGROUND AND PURPOSE Etiologic role, incidence, demographic, and response-to-treatment characteristics of urinary tract infection (UTI) among neonates, its relationship with significant neonatal hyperbilirubinemia, and abnormalities of the urinary system were studied in a prospective investigation in early (⩽10 days) idiopathic neonatal jaundice in which all other etiologic factors of neonata...

Etiology of Physiologic Neonatal Hyperbili­rubinemia. Every newborn infant develop·s hyperbilirubinemia during the first week of life which is called "physiologic". There are several factors responsible for the development of physiologic hyperbilirubinemia, as follows:  1. Increased bilirubin production, due to a - Increased blood volume. b - Decreased R.B.C. survival time.  c - Increased in...

Background: Neonatal hyperbilirubinemia is indeed common. However, severe nerve injuries and bilirubin encephalopathy are rare and only occur in the unusual cases of extreme hyperbilirubinemia. Objectives: To investigate brain magnetic resonance imaging (MRI) changes and their correlations with perinatal predisposing factors in neonates with indirect hyperbilirubinemia, via regions of interest ...

This article discusses the production, transport, and excretion of bilirubin in the newborn period. The causes, significance, and treatment of unconjugated and conjugated hyperbilirubinemia are different; and because this is so, it is important to review the main causes and management of unconjugated hyperbilirubinemia. Conjugated hyperbilirubinemia in the newborn period could be either due to ...

Severe hyperbilirubinemia in a pregnant mother suffering from Crigler-Najjar syndrome type II is a threat to the unborn child and may result in brain injury. We report the case of a Gly71-->Arg/Tyr486-->Asp homozygous mother of East Asian descent, who was treated with phototherapy during embryogenesis and with phenobarbital during the rest of the pregnancy. This resulted in significantly reduce...

Background: Hyperbilirubinemia in newborn is quite common. Phototherapy (PT) one of the most common noninvasive methods for treatment this hyperbilirubinemia. There are limited studies available on effect PT platelet count with contrasting results. So, study was conducted to determine phototherapy counts hyperbilirubinemic neonates tertiary care hospital. Methods: This a hospital based prospect...