T HE effects of exogenous progesterone on the corpus luteum are quite variable. No gross or microscopic effects were apparent in the pregnant rat (Sammelwitz et al., 1956; Aldred et al., 1959) or rabbit (Ulberg, 1952). Selye (1939) reported no effect of progesterone on corpora lutea of late pregnancy in mice, but Burdick (1942) found that treatment begun one or two days post-mating caused lutea...