Interactions between biological vulnerability and environmental adversity are central to the pathophysiology of depression. Given evidence that the hypothalamic-pituitary-adrenal (HPA) axis influences biological responses to environmental events, in the current longitudinal study the authors examined HPA-axis functioning, negative life events, and their interaction as predictors of the first on...

BACKGROUND The relationship of demographic factors and negative life events to the mental health of mainland Chinese school students has not been fully explored. AIM Assess the prevalence of different types of life stressors among secondary school students and identify the demographic characteristics and types of life events that are most closely associated with perceived psychological diffic...

BACKGROUND The relationship between stress and quality of life in adults with asthma has not been well studied. Stress, quantified by negative life events, may be linked to quality of life in asthma through multiple pathways, including increase in disease severity and adverse effects on socioeconomic status (SES). METHODS The responses to a self-completed questionnaire assessing negative life...

Diatheses Vulnerability factors that increase the stressfulness and negative consequences of life events. Difficulties Ongoing stressful situations that persist for at least 3 months. Independence The degree to which a person’s behavior or characteristics might have brought about a stressful life event. Matching events Acute major negative events that arise from or are thematically related to o...

In the present study, we examined loneliness and negative life events as predictors of suicide risk (viz., hopelessness and suicidal behaviors) in a sample of 160 Hispanic adults. Consistent with expectations, we found loneliness and negative life events to be positively associated with both hopelessness and suicidal behaviors. In addition, results of conducting hierarchical regression analyses...

The present study was conducted on a large sample of Chinese medical students to test the moderating effect of resilience between negative life events and mental health problems, and investigate the factors that affect the mental health problems of the students. The Adolescent Self-Rating Life Events Check List, Eysenck Adult Personality Questionnaire-Revised, Social Support Rating Scale, Conno...

In a cross-sectional study, we examined the role of explanatory styles and negative life events in the depressive experiences of AI youth. Ninetythree AI youth (49% female, ages 11-14 years) completed surveys assessing for explanatory style, negative life events, and depressive symptoms. Path analyses indicated that both the occurrence of negative life events within the past 6 months and a pess...

arm have an annual x ray or nothing other than simple follow-up. The contamination rate for the control arm (ie, having a sneak chest radiograph or even a privately paid computed tomogra-phy) is not known, although this reached in excess of 50% in the chest radiograph versus nothing randomised controlled trial led by the Mayo Clinic in the 1950s. Into this area of uncertainty comes a most inter...