We have recently shown that a polyphenol-rich insoluble dietary fibre preparation from carob pulp (Ceratonia siliqua L; carob fibre) decreased postprandial acylated ghrelin, TAG and NEFA during an acute liquid meal challenge test. However, delayed effects of carob fibre consumption are unknown. Therefore, a randomized controlled crossover study in nineteen healthy volunteers consuming foods wit...

Relative exercise intensity (or %maximum O2 consumption,V˙o 2 max) controls fuel selection at sea level (SL) and after high-altitude acclimation (HA) in rats. In this context we used indirect calorimetry, [1-14C]palmitate infusions, and muscle triacylglycerol (TAG) measurements to determine 1) total lipid oxidation, 2) the relationship between circulatory nonesterified fatty acid (NEFA) flux an...

Obesity has been associated with dysfunctional postprandial adipose tissue blood flow (ATBF), but it has also been recognized that the interindividual response is highly variable. The present work aimed at characterizing this variability. Fifteen subjects were given 75 g oral glucose, and abdominal subcutaneous ATBF was monitored by the (133)Xe washout method. Determinants of insulin sensitivit...

Received: Revised: Accepted: Published online: September 16, 2016 January 05, 2017 February 04, 2017 March 11, 2017 Body condition score (BCS) changes and non-esterified fatty acids (NEFA) are good indicators for measuring lipomobilization during the transition period. The aim of this study was to establish the possible correlation between cows with a higher BCS during this period and their rep...

A polymorphism in FABP2 that results in an alanine-to-threonine substitution at amino acid 54 of the intestinal fatty acid-binding protein (IFABP) is associated with insulin resistance in Pima Indians. In vitro, the threonine form (Thr54) has a higher binding affinity for long-chain fatty acids than does the alanine form (Ala54). We tested whether this polymorphism affected metabolic responses ...

BACKGROUND Ketosis-prone diabetes (KPDM) is new-onset diabetic ketoacidosis without precipitating factors in non-type 1 diabetic patients; after management, some are withdrawn from exogenous insulin, although determining factors remain unclear. METHODS Twenty KPDM patients and twelve type 1 diabetic patients (T1DM), evaluated at baseline, 12 and 24 months with/without insulin maintenance unde...

Most dairy cows experience a period of energy deficit in early lactation, resulting increased plasma concentrations nonesterified fatty acids (NEFA) and β-hydroxybutyrate (BHB). Our objectives were to determine (1) the diurnal variation BHB NEFA, (2) correlation between NEFA when accounting for changes, (3) effect hyperketonemia (HYK) on pattern blood metabolites. Jugular catheters placed 28 mu...

The study was conducted to compare the haematological, biochemical and nutritional parameters between healthy foals (HF) weak (WF, malformation, lameness drooping ears), corresponding female donkeys provide a reference for assessment of status. A total 34 with HF (DHF) WF (DWF) were selected. Compared HF, had higher leukocyte, neutrophil, platelets (PLT) percentage their showed similar tendency...

OBJECTIVE In end-stage renal failure, dyslipoproteinemia is linked to risk of cardiovascular disease. Increased concentrations of triacylglycerol-rich, very low density lipoproteins (VLDL) and decreased concentrations of high density lipoproteins (HDL) are usual, whilst total cholesterol and low density lipoprotein (LDL) concentrations are not increased. Non-esterified fatty acids (NEFA) are no...