During 2006 and 2007, forages from 3 individual hay harvests were utilized to assess the effects of spontaneous heating on concentrations of fiber components, 48-h neutral detergent fiber (NDF) digestibility (NDFD), and in situ disappearance kinetics of NDF for large-round bales of mixed alfalfa (Medicago sativa L.) and orchardgrass (Dactylis glomerata L.). Over the 3 harvests, 96 large-round b...

Increasing use of electronic health records requires comprehensive patient-centered views of clinical data. We describe a prototype knowledge base and SMART app that facilitates organization of patient medications by clinical problems, comprising a preliminary step in building such patient-centered views. The knowledge base includes 7,164,444 distinct problem-medication links, generated from Rx...

A new in vitro lab assay has been developed by UW-Madison Dairy Scientists that predicts total tract NDF digestion in ruminants. The in vitro TTNDFD assay predicts NDF digestion of alfalfa, corn silage, grass forages and byproduct feeds. UW-Madison researchers have validated the accuracy of the in vitro TTNDFD test against directly measured NDF digestibility lactating dairy cattle. The Universi...

Neu differentiation factor (NDF, also called heregulin) is a 44-kilodalton glycoprotein that stimulates tyrosine phosphorylation of the Neu/HER-2 receptor and induces phenotypic differentiation of certain mammary cancer cell lines to growth-arrested and milk-producing cells. To determine which molecules participate in the concomitant morphological alterations, we analyzed the expression of seve...

This study compared the effects of drying on beet pulp with and without added molasses by measuring the in sacco digestibility and composition including ®ber polysaccharides and minerals. Beet pulp was sampled before and after the addition of molasses from four different sugar processing plants within California. These samples were sub-sampled and then sun-, freeze-, or airdried. The percentage...

ion, while GLIF supports temporal operators of the Arden Syntax logic grammar SQL that supports some first-order logic criteria An embedded health record model UMLS & SNOMED [33] 2004 GLIF3 No GELLO: an expression language that defines the syntax and semantics of the decision criteria. It is defined by HL7 and CDISC. HL7 RIM (Reference Information Model) UMLS [34] 2007 SAGE A rich set of criter...

In this study, we compared the gene expression profiles of non-syndromic hyperplastic dental follicle (HDF) fibroblasts and normal dental follicle (NDF) fibroblasts using cDNA microarrays, quantitative PCR, and immunohistochemical staining. Microarray analysis showed that several collagens genes were upregulated in the HDFos, including collagen types I, IV, VIII, and XI and TIMP-1, -3, and -4 (...

We show how to learn low-dimensional representations (embeddings) of a wide range of concepts in medicine, including diseases (e.g., ICD9 codes), medications, procedures, and laboratory tests. We expect that these embeddings will be useful across medical informatics for tasks such as cohort selection and patient summarization. These embeddings are learned using a technique called neural languag...

OBJECTIVE In the 6 years since the National Library of Medicine began monthly releases of RxNorm, RxNorm has become a central resource for communicating about clinical drugs and supporting interoperation between drug vocabularies. MATERIALS AND METHODS Built on the idea of a normalized name for a medication at a given level of abstraction, RxNorm provides a set of names and relationships base...

The 2013 "Vaccine and Drug Ontology Studies" (VDOS 2013) international workshop series focuses on vaccine- and drug-related ontology modeling and applications. Drugs and vaccines have contributed to dramatic improvements in public health worldwide. Over the last decade, tremendous efforts have been made in the biomedical ontology community to ontologically represent various areas associated wit...