genome-wide association studies (gwas) have identified genetic variants contributing to the risk of cardiovascular disease (cvd) at the chromosome 9p21 locus. the chromosome 9p21 is an important susceptibility locus for several multifactorial diseases like ischemic stroke, aortic aneurysm, type 2 diabetes mellitus and coronary artery disease (cad). f7 gene because of its role in activating the ...

BACKGROUND Anopheles sinensis (Diptera: Culicidae) is a primary vector of Plasmodium vivax and Brugia malayi in most regions of China. In addition, its phylogenetic relationship with the cryptic species of the Hyrcanus Group is complex and remains unresolved. Mitochondrial genome sequences are widely used as molecular markers for phylogenetic studies of mosquito species complexes, of which mito...

introduction: endometriosis is a prevalent gynecological disorder among women which is diagnosed by the growth of endometrial tissue outside of uterus and is mainly accompanied by severe pelvic pain and infertility. p53 also known as cellular tumor antigen p53 inside codons 11, 72 and 248 are contained with single nucleotide changes in which tends to be nearly rampant.this will probably be incr...

results slow and fast-growing groups of the mycobacterium strains were clearly differentiated based on the constructed tree of 56 common mycobacterium isolates. each species with a unique title in the tree was identified; in total, 13 nods with a bootstrap value of over 50% were supported. among the slow-growing group was mycobacterium kansasii, with m. tuberculosis in a cluster with a bootstra...

no abstract is provided.

introduction: cryptorchidism has been proved to cause apoptosis in germ cells in respond to changes in the stimulation levels of specific physiological events. the purpose of this study was to determine whether treatment of bilateral cryptorchidism was associated with alterations in testicular gene expression. methods: to induce bilateral cryptorchid model, immature mice were anesthetized and a...

idiopathic chronic urticaria (icu), the most common form (70-80%) of chronic urticaria is supposed to have immune basis causes. it is speculated that the promoter polymorphism of tgf-β1 gene may be involved in icu. this condition is thought to affect at least 0.1% of the population and often can be severe and difficult to treat. a total of 40 patients with icu and 41 normal subjects were studie...

identification of genes with invariant levels of gene expression is a prerequisite for validating transcriptomicchanges accompanying development. ideally expression of these genes should be independent of themorphogenetic process or environmental condition.we report here the validation of internal control genei.e.tps (trehalose 6-phosphate-synthase) in cotton (gossypium spp), using taqman syste...