Results of broadband dielectric spectroscopy (BDS) in Saccharomyces cerevisiae (baker's yeast), in situ as the function of pressure are presented. They show a clear evidence of a threshold to the new pattern of the pressure evolution of the static dielectric permittivity and DC electric conductivity already for Pt  ≈ 200MPa at T = 5 oC and Pt  ≈ 300MPa at T = 25 oC. BDS monitoring versus pressu...

ll is now accepted that inhaled bronchodilator therapy is, whenever possible, to be preferred to oral treatment in the routine management of reversible airflow obstruction [1). However, during the last two decades we have repeatedly been reminded that many patients have great difficulty in using the conventional pressurized metered dose inhaler (MDI) [2-6], today's most frequently prescribed in...

The absolute systemic availability and pulmonary deposition of budesonide inhaled from a pressurized metered-dose inhaler (pMDI) attached to a Nebuhaler spacer was determined in 15 healthy subjects. The study was of an open cross-over design. Each subject randomly received three single doses of budesonide on separate days: 0.5 mg given intravenously and 1.0 mg (0.2 mg x 5) by inhalation from a ...

To investigate alternative mechanisms generating artificial circulation during cardiopulmonary resuscitation (CPR), an electrical model of the circulation was developed. Heart and blood vessels were modeled as resistive-capacitive networks; pressures in the chest, abdomen, and vascular compartments as voltages; blood flow as electric current; blood inertia as inductance; and the cardiac and ven...

OBJECTIVE Assess paranasal sinus distribution of topical solutions following endoscopic sinus surgery (ESS) using various delivery devices. STUDY DESIGN Experimental prospective study. SUBJECTS AND METHODS Ten cadaver sinus systems were irrigated with Gastroview before surgery, after ESS, and after medial maxillectomy. Delivery was via pressurized spray (NasaMist), neti pot (NasaFlo), and s...

This paper presents a computational study of the fluid-structure interaction (FSI) mechanism in pressurized commodity tank cars in railroad application. Within the Lagrangian framework of Abaqus/Explicit, finite element analysis (FEA) is conducted to predict the structural response of tank cars under dynamic impact loading. A three-phase approach is adopted that explicitly models pressurized ga...

Crude brain homogenates of terminally diseased hamsters infected with the 263 K strain of scrapie (PrP Sc) were heated and/or pressurized at 800 MPa at 60 degrees C for different times (a few seconds or 5, 30, 120 min) in phosphate-buffered saline (PBS) of different pH and concentration. Prion proteins were analyzed on immunoblots for their proteinase K (PK) resistance, and in hamster bioassays...

OBJECTIVES To report a case of extensive subcutaneous emphysema introduced during vitrectomy while using an advanced feedback-controlled pressurized infusion system. METHODS Clinical case report of a 56-year-old woman undergoing pars plana vitrectomy for rhegmatogenous retinal detachment of the left eye. The clinical and radiologic findings of the patient's eyes were documented. The mechanism...

This study assessed whether the improper use of pressurized metered-dose inhalers (pMDIs) is associated with decreased asthma control in asthmatics treated by inhaled corticosteroids (ICS). General practitioners (GPs) included consecutive asthmatic outpatients treated by pMDI-administered ICS and on-demand, short-acting beta2-agonists. They measured an asthma instability score (AIS) based on da...

PURPOSE We aimed to investigate the cardiopulmonary effects of pressurized cement insertion in elderly patients undergoing cemented hip hemiarthroplasty. MATERIALS AND METHODS We conducted a randomized prospective study on elderly patients undergoing cemented hip hemiarthroplasty. Patients were divided into pressurized and non-pressurized groups based on the pressure application during cement...