Bottom-up approach is a potentially useful tool for hydrogel assembly of cell-laden individual building blocks. In this article, we assembled individual building blocks of photocrosslinkable microgels in a rapid and controlled manner. Individual building blocks of poly(ethylene glycol) (PEG) microgels with square and hexagonal shapes were fabricated by using a photolithography technique. Indivi...

The aim of this research was to prepare a novel sponge-like porous hydrogel scaffold based on human-like collagen (HLC) that could be applied in cartilage tissue regeneration. In this study, bovine serum albumin (BSA) was used as a porogen to prepare the porous hydrogel, which had not been previously reported. Glutamine transaminase (TGase) was used as the cross-linker of the hydrogel, because ...

Postoperative peritoneal adhesion is one of the serious issues because it induces severe clinical disorders. In this study, we prepared biodegradable and injectable hydrogel composed of N,O-carboxymethyl chitosan (NOCC) and aldehyde hyaluronic acid (AHA), and assessed its anti-adhesion effect in a rigorous and severe recurrent adhesion model which is closer to clinical conditions. The flexible ...

Soft matter, which is sensitive to weak interaction and easily deformed by external stimuli, plays essential roles in natural sensing systems. For example, the allosteric effect of protein in ion channels dominates the selective ion transportation in cellular processes. [ 1 ] Inspired by natural systems, a wide variety of artifi cial sensing systems have been constructed from soft matter. Recen...

A simple and efficient approach for concentration of charged molecules in microfluidic devices is described. The functional component of the system is a hydrogel microplug photopolymerized within the main channel of a microfluidic device. When an appropriately biased voltage is applied across the hydrogel, charged analyte molecules move from the source well toward the hydrogel. Transport of the...

A hydrogel is a water-insoluble three-dimensional polymer network that has the ability to absorb body fluids in biological environment. Such formed through chemical crosslinking mechanisms such as optical polymerization, enzymatic reactions and physical temperature pH dependent processes ionic crosslinking. Physical hydrogels are weak secondary force by covalent forces. Various polymers of natu...

Current research is moving towards iron and ammonia elimination from groundwater. Here, we are using a poly acrylic–poly acrylamide hydrogel that grafted with 3-chloroaniline. This copolymer was synthesized by addition polymerization technique. The effects of agitation time, dosage adsorbent temperature on the removal process sensitivity were investigated. described experientially theoretically...

This study investigated the encapsulation of newt iris pigment epithelial cells (PECs), which have the ability to regenerate a lens by trans-differentiation in vivo, within a biodegradable hydrogel of oligo(poly(ethylene glycol) fumarate) crosslinked with poly(ethylene glycol)-diacrylate. Hydrogel beads of initial diameter of 1 mm were fabricated by a molding technique. The swelling ratio and d...

Synthetic polymer was exploited as water-superabsorbent hydrogel and helped to conserve water in the agricultural soil. The hydrogel polymers were synthesized the carboxymethyl cellulose (CMC) and starch in addition to SiO2 nanoparticles. Superabsorbent hydrogel polymer having 35% water retention ability was analyzed with three replicates. Hydrogel increased the water restoration capability of ...

The deformation behavior of a pH-sensitive hydrogel micro-fluidic valve system is investigated using inhomogeneous gel deformation theory, in which the fluid-structure interaction (FSI) of the gel solid and fluid flow in the pipe is considered. We use a finite element method with a well adopted hydrogel constitutive equation, which is coded in commercial software, ABAQUS, to simulate the hydrog...