this study took an epidemiological approach toward the problem of drug addiction in tehran. the subjects were 300 addicts chosen on the basis of stratified random selection out of the population of 3627 prisoners who were all proven addicts and sentenced to imprisonment by the court in the year 1370. a descriptive survey showed that drug addiction generally, and heroin addiction specifically, i...

Deafferentation pain is known usually to be resistant to both narcotic and non-narcotic analgesics. Four cases of this condition are reported here in which benefit was obtained with pizotifen, a 5-hydroxytryptamine antagonist. Further controlled clinical studies are required to verify this observation.

IMPORTANCE Laparoscopic ventral hernia repair (LVHR) using mesh is a well-established intervention for ventral hernia, but pain control can be challenging. OBJECTIVE To determine whether instillation of a long-acting local anesthetic between the mesh and the peritoneum after LVHR reduces pain or narcotic requirements. DESIGN, SETTING, AND PARTICIPANTS A prospective, double-blind, randomized...