نتایج جستجو برای: nanomicelles

تعداد نتایج: 226  

2017
Xiaocui Fang Hanyi Xie Hongyang Duan Ping Li Maryam Yousaf Haiyan Xu Yanlian Yang Chen Wang

Cancer is the leading cause of death worldwide, and metastasis is the main attribute to cancer death. CXCR4 and its natural ligand CXCL12 have been known to play a critical role in tumorigenesis, angiogenesis and metastasis. Therefore, designing a new CXCR4 antagonist to prevent tumor metastasis will be of great significance. Herein, a novel chemically synthesized peptide (E5) that has an abili...

Journal: :Polymers 2021

Age-related macular degeneration is a multifactorial disease affecting the posterior segment of eye and characterized by aberrant nascent blood vessels that leak fluid. It ends with vision loss. In present study, artemisinin which poorly water-soluble has potent anti-angiogenic anti-inflammatory properties was formulated into nanomicelles for its ocular application activity using CAM assay. Art...

Journal: :Cancer Nanotechnology 2022

Abstract Background Multi-drug delivery system based on polymer carrier is emerging for alleviating dose-limiting toxicities of first-line cytotoxic anticancer drugs, such as doxorubicin (DOX) breast cancer chemotherapy. By co-loading the premium natural antioxidant salvianolic acid A (SAA) through colloidal self-assembly amphiphilic copolymer, we herein developed CPMSD, a complex polymeric mic...

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