نتایج جستجو برای: nanobodies

تعداد نتایج: 541  

Journal: :Advanced therapeutics 2023

Applications of antibody-drug conjugates are rapidly growing, however, arduous fabrication antibodies and impairment highly potent drugs by covalent fixation to the protein is urging for alternatives these conventional strategies. Here, we demonstrate a procedure on genetically engineered single domain antibodies, so-called nanobodies, their site-specific reversible bioconjugation using self-im...

Journal: :Molecular Immunology 2021

Epithelial cell adhesion molecule (EpCAM) plays an important role in tumorigenesis. Camelids produce functional antibodies composed of heavy chains only that bind to their antigens via a single domain variable fragment known as nanobody. Nanobodies show multiple advantages over traditional monoclonal antibodies. Isolation anti-EpCAM nanobodies (Nbs) was the main aim this study. An immune nanobo...

Journal: :Bionatura (Ibarra - Impresa) 2023

The heavy chain fraction present in Camelidae antibodies is so-called nanobodies. They have different characteristics when compared to immunoglobulin G, like more diminutive size, higher affinity, shorter half-life serum, etc. These proteins are codified by B lymphocytes cDNAs and can be produced hosts Escherichia Coli, Pichia Pastoris, plant cells even insect cells. Andean camelids been mainly...

ژورنال: دانشور پزشکی 2011
احمدوند, داود , رهبری‌زاده, فاطمه , زرکش اصفهانی, سید حمید , مینائیان, سارا ,

Background and Objective: The human papillomavirus (HPV) is the main cause of cervical cancer. The symptoms of the disease are non-specific and it can be transferred from one person to another one. In order to prevent the spread of HPV virus and reducing mortality rate of cervical cancer, early detection programs are needed. Accurate and highly sensitive test is essential for screening examinat...

Journal: :Methods and Applications in Fluorescence 2015

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