Gadolinium (Gd)-based contrasts remain one of the most accepted contrast agents for magnetic resonance imaging, which is among the world most recognized noninvasive techniques employed in clinical diagnosis of patients. At ionic state, Gd is considered toxic but less toxic in chelate form. A variety of nano-carriers, including gadolinium oxide (Gd2O3) nanoparticles have been used by researchers...

Background The aim of present study was to evaluate antileishmanial effects of Lavandula angustifolia (L. angustifolia) and Rosmarinus officinalis (R. officinalis) medicinal plants essential oils and nano-emulsions on Leishmania major (L. major). Methods The present study was performed in Leishmaniasis Reference Lab at Mazandaran University of Medical Sciences, Iran during 2016-2017. The IC50...

Today’s, nanotechnology is integral part of pharmaceutics and Drug delivery system. In pharmaceutical science size is an important matter because it influences the drugs bioavailability; toxicity reduction; and better formulation. Nano size enhances drug performance many fold. It provides intelligent systems, devices and materials for better pharmaceutical applications. This review paper focuse...

Tubulysins, linear tetrapeptides produced by several strains of myxobacteria, show an extremely high toxicity towards a wide range of cancer cell lines, with IC50 values in the nano or even picomolar range. Therefore, tubulysins and their derivatives might be suitable candidates for the development of antitumor drugs. Several synthetic approaches for tubulysins and derivates have been developed...

This study focuses on interactions between nanoparticles and a pesticide. The aim was to investigate how nano-sized aluminum oxide (410 nm) can alter the toxic effects of thiacloprid, even if no sorption between particles and the insecticide takes place. Thus, our study investigated a rather unexplored interaction. We conducted our research with larvae of Chironomus riparius and used thiaclopri...

OBJECTIVES We sought to establish a novel method to generate nano-sized carbon black particles (nano-CBPs) with an average size smaller than 100 nm for examining the inhalation exposure risks of experimental rats. We also tested the effect of nano-CBPs on the pulmonary and circulatory systems. METHODS We used chemical vapor deposition (CVD) without the addition of any additives to generate na...

Implication for health policy/practice/research/medical education: Provide scientific knowledge regarding handling and application of Nano particles in medicine. which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. In recent years Nano-structure materials have been attractive to the world of science and technology for their...

Cisplatin (cis-(diammine)dichloridoplatinum(II)) is the first platinum-based compound approved by United States Food and Drug Administration (FDA) (U.S.). This a first-line chemotherapeutic treatment used alone or combined with other anticancer drugs to treat broad spectrum of malignancies, cisplatin-based nano-formulations currently in clinical studies. has several drawbacks, including low aqu...

background: the presence of heavy metals in the environment especially in water supplies have caused many concerns because of their toxicity and non-degradability. hexavalent chromium (cr) is one of the most toxic metals which is used in many industries, so it is essential to remove it from industrial wastewater. in this study, we made a comparison between different adsorption isotherms in the ...