Diabetes Mellitus (DM) has emerged as an epidemic that affected millions of people globally in the last few decades. Conventional antidiabetic dosage forms have a lot problems necessitate searching for novel drug delivery systems to overcome these drawbacks. Niosomes and proniosomes been used carry wide variety drugs achieving controlled sustained release, which improves patient compliance. Thi...

this study aims to investigate the capability of forming itraconazole containing niosomes with span 60 and brij 58 as non-ionic surfactants. lower cost and higher stability makes niosomes a more suitable choice in comparison with liposomes.the capability to form vesicles as an itraconazole delivery system and the influence of different factors such as type of surfactant and molar ratio of chole...

in this study canthaxanthin was produced by dietzia natronolimnaea hs1 and used for incorporation in niosomes after extraction. effect of rotational speed of rotary vacuum evaporator flask (100 and 150 rpm), canthaxanthin concentration (0, 1 and 2 microgram/ milliliter), concentration of poly ethylene glycol 400 (0, 0.1 and 0.2 %), surfactant type (tween 60 and 80, span 60 and 80) and surfactan...

Span 20-based niosome was prepared by lipid film hydration technique and loaded with Newcastle disease vaccine. Three batches with Span 20, cholesterol and dicetyl phosphate in micro molar ratios of 10:10:1; 15:15:1 and 20:20:1 were prepared and evaluated for encapsulation efficiency using haemagglutination test. The morphology of the vesicles was studied by means of transmission electron micro...

Objective(s): The purpose of the present study was to prepare and to evaluate a novel niosome as transdermal drug delivery system for propranolol hydrochloride and to compare the in vitro efficiency of niosome by either thin film hydration or hand shaking method. Materials and Methods: Niosomes were prepared by Thin Film Hydration (TFH) or Hand Shaking (HS) method. Propranolol niosomes were pre...

The potency of nanoparticles, loaded with drugs, genes, and/or diagnostics, is frequently depending upon their morphology adopted in a biological relevant environment. Freeze-fracture electron microscopy is a powerful techniques to monitor the self-assembling of lipid-, polymer-, as well as protein/peptide-based drug and gene carries on a nano-size resolution scale. Freeze-fracture electron mic...

Niosomes are non-ionic surfactant vesicles inclosing an aqueous phase and a wide range of molecules could be encapsulated within aqueous spaces of lipid membrane vesicles. They are microscopic lamellar structures formed on the admixture of a non-ionic surfactant, cholesterol and phosphate with subsequent hydration in aqueous media. Niosomes belongs to novel drug delivery system which offers a l...