نتایج جستجو برای: nano micelle curcumin

تعداد نتایج: 65228  

2013
MUHAMAD SAHLAN

Propolis is strong adhesive material with one of most valuable bees product and has wide range of biological activities such as antibacterials, antiviruses, antifungals, antiinflammation, photoprotector and so on. Propolis has been aplied as antimicrobials agent in food and healtcare products. To improve handling properties, Indonesian propolis were encapsulated by casein micelle with a homogen...

2017
WG Singleton AM Collins AS Bienemann CL Killick-Cole HR Haynes DJ Asby CP Butts MJ Wyatt NU Barua SS Gill

BACKGROUND The pan-histone deacetylase inhibitor panobinostat is a potential therapy for malignant glioma, but it is water insoluble and does not cross the blood-brain barrier when administered systemically. In this article, we describe the in vitro and in vivo efficacy of a novel water-soluble nano-micellar formulation of panobinostat designed for administration by convection enhanced delivery...

Journal: :Journal of Drug Delivery Science and Technology 2022

The copper(I)-catalyzed azide/alkyne cycloaddition is recognized as one of the most successful click reactions to access self-assembling amphiphilic polymer-drug conjugates (PDCs). In this way, poor water-soluble drugs can be linked covalently hydrophilic poly(ethylene glycol) (PEG) obtain PEGylated drug micelles that used versatile carriers for delivery diverse therapeutic agents. work, two no...

2017
Yuki Hiruta Yuki Kanda Naoya Katsuyama Hideko Kanazawa

We report a polymeric micelle drug delivery system, which enables selective intracellular uptake with external thermal stimulation, and effective release of a drug at internal acidic endosomal pH. We developed a dual temperatureand pH-responsive polymeric micelle composed of a temperatureresponsive corona segment with poly(N-isopropylacrylamide-co-dimethylacrylamide) [P(NIPAAm-coDMAAm)] and a p...

Journal: :Journal of food research 2021

Stable oil-in-water nanoemulsions were generated by ultra-high-pressure homogenization (UHPH) at 140 and 210 MPa for use as nano-vesicular vehicles (NVV) to carry hydrophobic generally recognized safe (GRAS) curcumin (CU) whey protein isolate (WPI) in aqueous nutraceutical systems. Curcumin was used its antioxidant activity participation the Michael reaction with nucleophiles pHs above 8.0. Two...

2016
Haining Chen Fengbo Wu Jing Li Xuehua Jiang Lulu Cai Xiang Li

Prostate tumor cell targeted peptide fragment conjugated to the nano drug delivery system is a promising strategy for prostate cancer therapy. In this work, an amphiphilic copolymer Chol-PEG-DUP1 (PEG-cholesterol conjugated with DUP1 peptide) has been synthesized and characterized by proton nuclear magnetic resonance spectrum ((1)H NMR). The paclitaxel (PTX) was encapsulated into the Chol-PEG-D...

Journal: :Cancer biology & therapy 2011
Stephen Tuttle Lauren Hertan Joshua S Katz

474 Cancer Biology & Therapy Volume 11 Issue 5 Commentary to: Lim KJ, Bisht S, Bar EE, Maitra A, Eberhart CG. A polymeric nanoparticle formulation of curcumin inhibits growth, clonogenicity and stem-like fraction in malignant brain tumors. Cancer Biol Ther 2011; This issue.

Journal: :research in pharmaceutical sciences 0

single-walled carbon nanotubes (swnts) are among the promising nano-devices for delivery of therapeutic agents. yet the drastic hydrophobic natures of swnts make their handling and hence application difficult.several researches have been conducted to make them more hydrophilic and water dispersible and less toxic. among the different approaches, dispersion methods exploit different reagents suc...

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