Carbon nanoparticles can penetrate the cell membrane and cause cytotoxicity. The diffusion feature and translocation free energy of fullerene through lipid membranes is well reported. However, the knowledge on self-assembly of fullerenes and resulting effects on lipid membrane is poorly addressed. In this work, the self-assembly of fullerene nanoparticles and the resulting influence on the diol...

Alkyne-functionalized fullerenes (fullerynes) were designed and conveniently synthesized via Bingel reaction in one step with high yields. They were used to react with azido-functionalized polystyrene (PS) via Huisgen [3 + 2] cycloaddition 'click' chemistry to form two fullerene polymers: one with C60 tethered to the end of a PS chain (C60-1PS) and the other with C60 tethered at the junction po...

Oxygen adducts were among the first reported fullerene derivatives, and they have continued to be the subject of many subsequent investigations by experimental and theoretical researchers. A literature survey is presented summarizing the preparation, purification, characterization, and stabilities of fullerene oxides and ozonides. Published data on the 13C NMR spectra, thermal dissociation reac...

Twelve chiral and achiral self-assembling dendrons have been grafted onto a [60]fullerene hexa-adduct core by copper-catalyzed alkyne azide "click" cycloaddition. The structure adopted by these compounds was determined by the self-assembling peripheral dendrons. These twelve dendrons mediate the self-organisation of the dendronized [60]fullerene into a disc-shaped structure containing the [60]f...

Density Functional Theory has been used to model the Diels-Alder reactions of the fullerene fragments triindenetriphenilene and pentacyclopentacorannulene with ethylene and 1,3-butadiene. The purpose is to prove the feasibility of using Diels-Alder cycloaddition reactions to grow fullerene fragments step by step, and to dimerize fullerene fragments, as a way to obtain C₆₀. The dienophile charac...

MALDI LIFT-TOF/TOF mass spectra of fullerene C60 and six of its derivatives, methano[60]fullerene carboxylic acid, its ethyl ester, diethyl methano[60]fullerene dicarboxylate, and three isomeric tetraethyl bis-methano[60]fullerene tetracarboxylates (compounds I–VII, respectively) as model analytes were recorded and discussed. This technique used in mass spectrometry for the first time is propos...

Fullerene (C(60)), the third carbon allotrope, is a classical engineered material with the potential application in biomedicine. However, extremely high hydrophobicity of fullerene hampers its direct biomedical evaluation and application. In this work, we investigated the solubilization of fullerene using 9 different solubility enhancers: Tween 20, Tween 60, Tween 80, Triton X-100, PVP, polyoxy...

Antioxidants were implicated as potential reagents to enhance osteogenesis, and nano-fullerenes have been demonstrated to have a great antioxidative capacity by both in vitro and in vivo experiments. In this study, we assessed the impact of a polyhydroxylated fullerene, fullerol, on the osteogenic differentiation of human adipose-derived stem cells (ADSCs). Fullerol was not toxic against human ...

A fullerene graph F is a cubic 3-connected plane graph with exact 12 pentagons and other hexagons. Let M be a perfect matching of F . A cycle C of F is M -alternating if and only if the edges of C appear alternately in and off M . A set H of disjoint hexagons of F is called a resonant pattern if F has a perfect matching M such that all hexagons in H are M -alternating. A fullerene graph F is k-...

Nanotechnology offers many societal benefits and this have prompted the rapid growth of engineered nanomaterials. Fullerene (C60) due to its unique properties has become an important nanomaterial in biomedical and biotechnological applications. Once in water, Fullerene forms stable suspended aggregates and thus become bioavalable to aquatic biota. The fate and transport of fullerene in the aqua...