The effect of increasing concentrations of ivermectin on adenosine triphosphatase (ATPase) activity was investigated in adult worms of Onchocerca volvulus. Mean Mg- and Na,K-ATPase activities decreased significantly (F ratio = 29.82, P < 0.01 and F ratio = 28.54, P < 0.01, respectively) with increasing concentrations of ivermectin (0-100 ng/ml) in the female worms. When male and female worms we...

in wheat na+ exclusion and k+/na+ have shown to be associated with salinity tolerance, therefore in order to identify qtls with additive effect for na+ and k+ concentration traits in roots and shoots of wheat, 319  bread wheat recombinant inbred lines (ril f7), derived from a cross between roshan cultivar (salt tolerant) and falat cultivar (salt sensitive), along with their parents and 2 checks...

Na+/K(+)-ATPase activity was demonstrated in the midgut of Anopheles stephensi. More than 80% of the total ATPase activity was sensitive to inhibition by ouabain with an IC50 of 4.5 x 10(-7) +/- 0.3 x 10(-7) mol l-1 and with maximal inhibition occurring at 10(-4) mol l-1. This ouabain-sensitive Na+/K(+)-ATPase was maximally activated at a Mg2+:ATP ratio of 1:1.3, with a Km of 0.3 mmol l-1 and a...

background: garcinia kola seed is consumed indiscriminately in nigeria without recourse to its potential toxicity. therefore, this study was aimed at assessing the toxicity of the aqueous extract of g. kola seeds on selected tissues of male rats.  methods: thirty male rats (215.00 ± 18.58 g) were assigned into four groups: a, b, c and d which received 0.5 ml of distilled water, 25, 50 and 100 m...

background: electrolytes play an important role in the normal functioning of human body. electrolyte imbalance and mineral disturbances is the common clinical manifestation in several infectious diseases including malaria. malaria is a mosquito borne serious infectious disease of the world. plasmodium vivax and p. falciparum are the main agents responsible for malaria in pakistan. electrolyte i...

In this research, zeolite Na-Y was synthesized from Kaolin without an organic template under the non-hydrothermal condition to adsorb sulfur compound. Model fuel desulfurization was optimized by employing the Box-Behnken experimental design with 2 center points, the three parameters, and one response value. The objective was to find how sorption capacity is related to alkali fusion temperat...

INTRODUCTION Demographic and disease characteristics may impact response to psoriasis therapies. The objective of this study is to explore the safety and efficacy profile of secukinumab in North American (NA) versus non-NA patients with moderate to severe psoriasis. METHODS Data were pooled from four phase 3 studies of secukinumab. Secukinumab (300 and 150 mg) was administered at baseline, we...