PD-L1 has been characterized as an inhibitory immune checkpoint, leading to the suppression of potential anti-tumor activities in many cancer types. In view relatively limited efficacy checkpoint blockades against breast cancer, our recent study addressed possibility that addition its immune-inhibitory functions, promotes pro-metastatic cells themselves. Indeed, published findings demonstrated ...

Purpose: The emergence of COVID-19 and the measures put in place to curtail spread virus perceived hardship imposed on people prompted this study with view assess level awareness pandemic among residents Gwagwalada, examine their access basic health, social facilities identify needs support they received during lockdown.
 Methodology: A cross section survey research was employed a stratifi...

Quantum query complexity is a model of quantum computation, in which the cost of computing a function is measured by the number of queries that are made to the input given as a black-box. In this model, it was exhibited in the early stage of quantum computing research that there exist quantum algorithms superior to the classical counterparts, such as Deutsch and Jozsa’s algorithm, Simon and Sho...

Using a human non-immune phage library comprising more than 10(9) functional human antibody specificities in Fab format, we have been able to select a set of eight monoclonal Fabs targeted against diverse epitopes of the ectodomain of gp41 from HIV-1. The antigens used for panning the antibodies comprised two soluble, disulfide-linked, trimeric polypeptides derived from gp41, N(CCG)-gp41 and N3...

INTRODUCTION Radiation-induced xerostomia is a frequent late side effect after treatment for oral and oropharyngeal cancers. This may induce swallowing difficulties, compromised oral well-being, reduced nutrition intake, or speech deficiencies. Consequently, quality of life is often impaired for these patients. OBJECTIVES The purpose of this study was to investigate the possibility to mechani...