Wu, Feng, Frank Park, Allen W. Cowley, Jr., and David L. Mattson. Quantification of nitric oxide synthase activity in microdissected segments of the rat kidney. Am. J. Physiol. 276 (Renal Physiol. 45): F874–F881, 1999.—This study was designed to quantify nitric oxide synthase (NOS) activity in microdissected glomeruli (Glm), pars convoluta, pars recta, cortical collecting duct, cortical thick a...

Woods, Robyn L., and Marcus J. M. Jones. Atrial, B-type, and C-type natriuretic peptides cause mesenteric vasoconstriction in conscious dogs. Am. J. Physiol. 276 (Regulatory Integrative Comp. Physiol. 45): R1443–R1452, 1999.— Cardiovascular responses were compared with equimolar infusions of B-type (BNP) and C-type (CNP) with atrial natriuretic peptide (ANP) in conscious, instrumented dogs. On ...

Dall’Asta, Valeria, Ovidio Bussolati, Roberto Sala, Alessandro Parolari, Francesco Alamanni, Paolo Biglioli, and Gian C. Gazzola. Amino acids are compatible osmolytes for volume recovery after hypertonic shrinkage in vascular endothelial cells. Am. J. Physiol. 276 (Cell Physiol. 45): C865–C872, 1999.—The response to chronic hypertonic stress has been studied in human endothelial cells derived f...

Verberne, Anthony J. M., Daniela M. Sartor, and Ayse Berke. Midline medullary depressor responses are mediated by inhibition of RVLM sympathoexcitatory neurons in rats. Am. J. Physiol. 276 (Regulatory Integrative Comp. Physiol. 45): R1054–R1062, 1999.—Mechanisms underlying the depressor and sympathoinhibitory responses evoked from the caudal medullary raphe (MR) region were investigated in pent...

AKI YAMADA,1 SUSUMU OHYA,2 MASARU HIRANO,2 MINORU WATANABE,2 MICHAEL P. WALSH,3 AND YUJI IMAIZUMI1 1Department of Pharmacology and Therapeutics and 2Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, Nagoya City University, Nagoya 467-8603, Japan; and 3Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Calgary, Calgary, Alberta T2N 4N1, Ca...

Eaton, Philip, Jian-Mei Li, David J. Hearse, and Michael J. Shattock. Formation of 4-hydroxy-2-nonenalmodified proteins in ischemic rat heart. Am. J. Physiol. 276 (Heart Circ. Physiol. 45): H935–H943, 1999.—4-Hydroxy-2nonenal (HNE) is a major lipid peroxidation product formed during oxidative stress. Because of its reactivity with nucleophilic compounds, particularly metabolites and proteins co...

Kocsis, Bernat, Tomas Karlsson, and B. Gunnar Wallin. Cardiacand noncardiac-related coherence between sympathetic drives to muscles of different human limbs. Am. J. Physiol. 276 (Regulatory Integrative Comp. Physiol. 45): R1608–R1616, 1999.—Partial coherence analysis was used to evaluate the extent to which coherence between resting muscle sympathetic activity (MSA) in different pairs of limbs ...

Wyman, Bradley T., William C. Hunter, Frits W. Prinzen, and Elliot R. McVeigh. Mapping propagation of mechanical activation in the paced heart with MRI tagging. Am. J. Physiol. 276 (Heart Circ. Physiol. 45): H881–H891, 1999.— The temporal evolution of three-dimensional (3-D) strain maps derived from magnetic resonance imaging (MRI) tagging were used to noninvasively evaluate mechanical activati...

Kozma, Fruzsina, Robert A. Johnson, Fan Zhang, Changhua Yu, Xianglan Tong, and Alberto Nasjletti. Contribution of endogenous carbon monoxide to regulation of diameter in resistance vessels. Am. J. Physiol. 276 (Regulatory Integrative Comp. Physiol. 45): R1087–R1094, 1999.— Endogenous carbon monoxide was proposed to subserve vasodepressor functions. If so, inhibition of heme oxygenase may be exp...

Hypertension is the most common medical disorder of pregnancy in the United States, affecting 6% to 8% of pregnant women. It is also a leading cause of maternal and fetal morbidity and mortality worldwide1; approximately 63,000 women die every year because of the maternal hypertensive syndromes preeclampsia and eclampsia.2 Hypertensive disorders also result in fetal complications such as preter...