We found that ethyl gallate purified from a dried pod of tara (Caesalpinia spinosa) intensified beta-lactam susceptibility in methicillin-resistant and methicillin-sensitive strains of Staphylococcus aureus (MRSA and MSSA strains, respectively). This compound and several known alkyl gallates were tested with MRSA and MSSA strains to gain new insights into their structural functions in relation ...

Systematic investigations into the phase behavior of a ternary system of linear alkyl benzene sulfonate (LAS) or branched alkyl benzene sulfonate (BAS) in oil (corn or olive oil) and water were carried out. The study showed that there is a relationship between the surfactants’ chemical structure, aggregation properties, and the formation of micelles. The aggregation properties were dramatically...

Amine intercalated titanates were synthesized by direct exchange of potassium ions of K2Ti4O9 by alkyl ammonium ions of various alkyl chain lengths. These intercalated solids exfoliate well in alcohols of different alkyl chain lengths and non-polar solvents such as toluene and hexane to yield colloidal dispersions of titanate nanosheets. The longer the alkyl chain of the intercalated amine the ...

Vicinal stereocenters are found in many natural and unnatural compounds. Although metal-catalyzed cross-coupling reactions of unactivated alkyl electrophiles are emerging as a powerful tool in organic synthesis, there have been virtually no reports of processes that generate, much less control, vicinal stereocenters. In this investigation, we establish that a chiral nickel catalyst can mediate ...

The direct nucleophilic addition of alkyl amines to the α(δ')-carbon atom of dimethyl (E)-hex-2-en-4-ynedioate to generate α,β-dehydroamino acid derivatives is reported. Herein, we have studied the reactivity of various primary and secondary alkyl amines in the α-selective nucleophilic conjugate addition to conjugated dimethyl (E)-hex-2-en-4-ynedioate. The reaction with primary alkyl amines giv...

Introduction Long alkyl chains have a tendency to aggregate and form localized hydrophobic environments in polar solvent. This tendency has been exploited to prepare a variety of artificial structures, such as micelles, vesicles, core-shell structured polymers, and dendrimers, where the localized hydrophobic environments show interesting properties. These artificial long alkyl chain assemblies,...

Non-activated alkyl halides are challenging substrates for cross-coupling reactions because they are reluctant to undergo oxidative addition and because metal alkyl intermediates are prone to beta-H elimination. Despite recent progress, well-defined catalysts are rare. We recently prepared Ni complexes with a chelating pincer-type bis(amino)amide ligand. The chloride complex [((Me)NN2)NiCl] is ...

We determined the acyl and alkyl chain composition of GPI-anchors isolated from MDCK and Fischer rat thyroid (FRT) cells. Both cell lines synthesize GPI-anchors containing C16/C18 or C18/C18 saturated acyl and alkyl chains. The GPI-anchored placental alkaline phosphatase (PLAP) expressed in both cells is raft-associated and PLAP purified from FRT cells is raft-associated in vitro when reconstit...

Pneumocystis carinii carinii and rat lung phospholipids contained 3-6% 1-alkyl-2-acyl glycerols composed of the glyceryl ether species, 1-O-octadecyl glycerol (batyl alcohol), 1-O-octadec-9-enyl glycerol (selachyl alcohol), 1-O-hexadecyl glycerol (chimyl alcohol), and 1-O-hexadec-9-enyl glycerol. Of the major phospholipid classes, phosphatidylinositol (PI) and phosphatidylserine contained the h...