OBJECTIVES To investigate the relation between coronary flow reserve (CFR), coronary zero flow pressure (Pzf), and residual myocardial viability in patients with acute myocardial infarction. DESIGNS Prospective study. SETTING Primary care hospital. PATIENTS 27 consecutive patients with acute anterior myocardial infarction. MAIN OUTCOME MEASURES F-fluorodeoxyglucose (FDG) positron emissi...

Myocardial viability assessment is of utmost importance in the assessment of patients with poor left ventricular function undergoing revascularisation therapies or cardiac transplantation. Cardiac positron emission tomography (PET) is widely regarded as a "gold" standard in myocardial viability assessment. We review the current data on this subject with respect to tracers and techniques, and pr...

Ischemic cardiomyopathy results from severe extensive coronary artery disease, which is associated with left ventricular dysfunction and also, in many cases, with significant left ventricular dilatation. Mortality is high, especially in patients who satisfy myocardial viability criteria but who have not undergone revascularization. Although age, exercise capacity and comorbidity influence survi...

CMR is a rapidly developing new modality with applications in clinical cardiology for detection and assessment of myocardial ischemia and viability. CMR perfusion results for the detection of ischemia in comparison with stress echocardiography and scintigraphic techniques are reasonable, but all the studies reported to date have been conduced in selected patients. Larger studies in patient popu...

postsystolic motion or shortening predict recovery of myocardial function after primary percutanous coronary intervention?. J Am Soc Echocardiogr 2007;20: 505–11. 14. Lim P, Pasquet A, Gerber B, D’Hondt AM, Vancraeynest D, Gueret P et al. Is postsystolic shortening a marker of viability in chronic left ventricular ischemic dysfunction? Comparison with late enhancement contrast magnetic resonanc...

BACKGROUND We tested the hypothesis that multimodality imaging of mouse embryonic stem cells (mESCs) provides accurate assessment of cellular location, viability, and restorative potential after transplantation into different zones of myocardial infarction. METHODS AND RESULTS Mice underwent left anterior descending artery ligation followed by transplantation of dual-labeled mESCs with superp...

OBJECTIVE To investigate the diagnostic value of 18F-fluorodeoxyglucose positron emission tomography ((18)F-FDG PET) in the assessment of myocardial viability in patients with known coronary artery disease (CAD) when compared to (99m)Tc single photon emission computed tomography (SPECT) and echocardiography, with invasive coronary angiography as the gold standard. METHODS Thirty patients with...

Background. Stress thallium scintigraphy provides important diagnostic and prognostic information in patients with coronary artery disease by demonstrating regional myocardial ischemia. However, if the clinical question being addressed is whether a region is viable and not whether there is inducible ischemia, then it may be more reasonable to perform rest-redistribution imaging rather than stre...