نتایج جستجو برای: myocardial ischaemia reperfusion injury

تعداد نتایج: 470209  

2016
Esben Søvsø Szocska Hansen Steen Fjord Pedersen Steen Bønløkke Pedersen Uffe Kjærgaard Nikolaj Hjort Schmidt Hans Erik Bøtker Won Yong Kim

OBJECTIVE Microvascular obstruction (MVO) and intramyocardial haemorrhage (IMH) are known complications of myocardial ischaemia-reperfusion injury. Whereas MVO is an established marker for a poor clinical outcome, the clinical significance of IMH remains less well defined. Cardiovascular MR (CMR) and T2 weighted short tau inversion recovery (T2-STIR) imaging have been used to detect IMH and to ...

Journal: :Gut 2005
H Suetsugu Y Iimuro T Uehara T Nishio N Harada M Yoshida E Hatano G Son J Fujimoto Y Yamaoka

BACKGROUND In hepatic ischaemia/reperfusion injury, activated liver macrophages (Kupffer cells) are dominantly regulated by a transcription factor, nuclear factor kappaB (NFkappaB), with respect to expression of inflammatory cytokines, acute phase response proteins, and cell adhesion molecules. AIMS We assessed whether inactivation of NFkappaB in the liver could attenuate total hepatic warm i...

2005
H Suetsugu J Fujimoto Y Yamaoka

Background: In hepatic ischaemia/reperfusion injury, activated liver macrophages (Kupffer cells) are dominantly regulated by a transcription factor, nuclear factor kB (NFkB), with respect to expression of inflammatory cytokines, acute phase response proteins, and cell adhesion molecules. Aims: We assessed whether inactivation of NFkB in the liver could attenuate total hepatic warm ischaemia/rep...

2017
Yaqiong Wang Xiaoxiang Yan Shouling Mi Zhang Li Yuexiang Wang Hong Zhu Xiaolei Sun Buchang Zhao Chao Zhao Yunzeng Zou Kai Hu Xiaoqiang Ding Aijun Sun Junbo Ge

Naoxintong (NXT) is a Chinese Materia Medica standardized product extracted from 16 various kinds of Chinese traditional herbal medicines including Salvia miltiorrhiza, Angelica sinensis, Astragali Radix. Naoxintong is clinically effective in treating ischaemia heart disease. Nucleotide-binding oligomerization domain-Like Receptor with a Pyrin domain 3 (NLRP3) inflammasome has been critically i...

Journal: :British journal of anaesthesia 1992
P Colson A Galy D Grolleau J Séguin M Saussine D Cuchet P A Chaptal B Roquefeuil

We have studied the cardiovascular effects of nitrous oxide after cardiac ischaemia-reperfusion injury caused by aortic cross-clamping and unclamping during coronary artery bypass grafting (CABG). At the time of chest closure, 20 patients were allocated randomly to receive oxygen and air (FIO2 = 0.5) or 50% nitrous oxide in oxygen in addition to anaesthesia with fentanyl. Nitrous oxide signific...

Journal: :Clinical and investigative medicine. Medecine clinique et experimentale 2007
Sheng Kang Yuejin Yang

PURPOSE To review (1) the mechanisms of coronary microvascular reperfusion injury, particularly in the relationships between microvascular endothelium dysfunction, microstructure damage, microemboli and no-reflow phenomena; (2) the no-reflow presentation and management at ischemia-reperfusion to suggest future direction for no-reflow therapy in acute myocardial infarction. SOURCES Original ar...

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