نتایج جستجو برای: myeloid derived suppressor cell

تعداد نتایج: 2090781  

Journal: :Frontiers in Cellular and Infection Microbiology 2016

Journal: : 2023

Myeloid-derived suppressor cells (MDSCs) are a heterogeneous cell population that primarily suppress T lymphocytes in healthy pregnancies and pathologies. MDSCs one of the key regulators immune responses. Finding ways to control them is important for treatment cancer, autoimmune diseases, miscarriage, post-transplant complications. The mechanisms suppression by MDSC are: expression CD73, ADAM17...

2016
Vincenzo Bronte Sven Brandau Shu-Hsia Chen Mario P. Colombo Alan B. Frey Tim F. Greten Susanna Mandruzzato Peter J. Murray Augusto Ochoa Suzanne Ostrand-Rosenberg Paulo C. Rodriguez Antonio Sica Viktor Umansky Robert H. Vonderheide Dmitry I. Gabrilovich

Myeloid-derived suppressor cells (MDSCs) have emerged as major regulators of immune responses in cancer and other pathological conditions. In recent years, ample evidence supports key contributions of MDSC to tumour progression through both immune-mediated mechanisms and those not directly associated with immune suppression. MDSC are the subject of intensive research with >500 papers published ...

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