Mutual information (MI), a quantity describing the nonlinear dependence between two random variables, has been widely used to construct gene regulatory networks (GRNs). Despite its good performance, MI cannot separate the direct regulations from indirect ones among genes. Although the conditional mutual information (CMI) is able to identify the direct regulations, it generally underestimates th...

We present a methodology based on Information theory tools to optimize the operating temperatures of metal-oxide (MOX) gas sensor arrays and maximize the ability of the system in odor discrimination tasks. We have demonstrated the feasibility of the method by optimizing the temperatures of a foursensor array for an effective discrimination of four odorants. We measured the resistance of four MO...

Diffuse optical tomography (DOT) retrieves the spatially distributed optical characteristics of a medium from external measurements. Recovering the parameters of interest involves solving a nonlinear and highly ill-posed inverse problem. This paper examines the possibility of regularizing DOT via the introduction of a priori information from alternative high-resolution anatomical modalities, us...

The paper examines relationships between the conditional Shannon entropy and the expectation of `α-norm for joint probability distributions. More precisely, we investigate the tight bounds of the expectation of `α-norm with a fixed conditional Shannon entropy, and vice versa. As applications of the results, we derive the tight bounds between the conditional Shannon entropy and several informati...

Abstract—Alignment of biological sequences such as DNA, RNA or proteins is one of the most widely used tools in computational bioscience. One of the important research topics of bioinformatics is the multiple proteins sequence alignment. Since the exact methods for MSA have exponential time complexity, the heuristic approaches and the progressive alignment are the most commonly used in multiple...

Magneto-inductive (MI) waveguides are periodic structures that operate by magnetic coupling between a set of lumped-element L-C resonators. The effect of waveguide bending on the propagation of MI waves is investigated, and it is shown that discontinuities in axis curvature will typically generate reflections. Changes in the equivalent circuit parameters of two types of MI waveguides (formed fr...