نتایج جستجو برای: mutant

تعداد نتایج: 129581  

BACKGROUND: Canine Parvovirus (CPV) is one of the major causes of fatal gastroenteritis in young dogs. After emergence of CPV-2, two new variants were reported and named CPV-2a and CPV-2b. In 2001 the newest variant was reported and named CPV-2c. The difference between CPV strains is related to amino acid changes in viral capsid protein (VP2). OBJECTIVES: The aim of the present study was geneti...

Journal: :Antimicrobial agents and chemotherapy 2012
Sarah Harman Carolina Herrera Naomi Armanasco Jeremy Nuttall Robin J Shattock

Topical blockade of the gp41 fusogenic protein of HIV-1 is one possible strategy by which microbicides could prevent HIV transmission, working early against infection, by inhibiting viral entry into host cells. In this study, we examined the potential of gp41 fusion inhibitors (FIs) as candidate anti-HIV microbicides. Preclinical evaluation of four FIs, C34, T20, T1249, and L'644, was performed...

2010
Hirokazu Koizumi Masao Hashimoto Mamoru Fujiwara Hayato Murakoshi Takayuki Chikata Mohamed Ali Borghan Atsuko Hachiya Yuka Kawashima Hiroshi Takata Takamasa Ueno Shinichi Oka Masafumi Takiguchi

Journal: : 2022

Genetic Variation of Some Agronomic Characteristics and Grain Quality Traits Rice Mutant Genotypes

Journal: :Agronomy 2023

Plastid-encoded RNA polymerase (PEP) regulates the expression of chloroplast genes involved in photosynthesis and development rice. The PEP-associated protein (PAP) PAP7/pTAC14 is essential for formation PEP complex. However, function PAP7 rice remains unclear. In this study, we identified a mutant, w81, which displays yellow-green leaf symptom before four-leaf stage. seedlings w81 mutant displ...

Journal: :Studies in Applied Mathematics 2021

We consider a spatial (line) model for invasion of population by single mutant with stochastically selectively neutral fitness landscape, independent from the landscape non-mutants. This is similar to those considered in Farhang-Sardroodi et al. [PLOS Comput. Biol., 13(11), 2017; J. R. Soc. Interface, 16(157), 2019]. show that probability fixation size $N$, starting mutant, greater than $1/N$, ...

Journal: :FEBS Letters 2021

Acetate overflow refers to the metabolism by which a large part of carbon incorporated as glucose into Escherichia coli cells is catabolized and excreted acetate medium. We previously found that mutants for pathway enzymes phosphoacetyltransferase (Pta) kinase (AckA) showed significant diauxic growth after depletion in E. coli. Here, we analyzed underlying mechanism pta mutant. Proteomic other ...

Journal: :به نژادی گیاهان زراعی و باغی 0
زهرا مجیدی کارشناس ارشد، گروه بیوتکنولوژی و اصلاح نباتات، دانشکدۀ علوم زراعی، دانشگاه علوم کشاورزی و منابع طبیعی ساری غلامعلی رنجبر دانشیار، گروه بیوتکنولوژی و اصلاح نباتات، دانشکدۀ علوم زراعی، دانشگاه علوم کشاورزی و منابع طبیعی ساری نادعلی بابائیان جلودار استاد، گروه بیوتکنولوژی و اصلاح نباتات، دانشکدۀ علوم زراعی، دانشگاه علوم کشاورزی و منابع طبیعی ساری نادعلی باقری استادیار، گروه بیوتکنولوژی و اصلاح نباتات، دانشکدۀ علوم زراعی، دانشگاه علوم کشاورزی و منابع طبیعی ساری

in order to evaluate chemical mutation on cultivar mahali tarrom’ in salt stress, seeds of rice cultivar ‘mahali tarrom’ were treated with two chemical mutagens, ethyl methane sulfonate (14 mm) and sodium azide (two mm). in second generation, appropriate plants for economically important traits have been selected. seeding of selected plants were tested under salt stress in third generation usin...

2011
An-Jing Chen Shuai Wang Xiao-Fan Zhao Xiao-Qiang Yu Jin-Xing Wang

Recent studies have shown that the ubiquitin proteasome pathway (UPP) is closely related to immune defense. We have identified a ubiquitin-conjugating enzyme E2 from the Chinese white shrimp Fenneropenaeus chinensis (FcUbc). Injection of recombinant FcUbc protein (rFcUbc) reduced the mortality of shrimp infected with White Spot Syndrome Virus (WSSV) and inhibited replication of WSSV. rFcUbc, bu...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2002
Alexandra Trkola Shawn E Kuhmann Julie M Strizki Elizabeth Maxwell Tom Ketas Tom Morgan Pavel Pugach Serena Xu Lisa Wojcik Jayaram Tagat Anandan Palani Sherry Shapiro John W Clader Stuart McCombie Gregory R Reyes Bahige M Baroudy John P Moore

To study HIV-1 escape from a coreceptor antagonist, the R5 primary isolate CC1/85 was passaged in peripheral blood mononuclear cells with increasing concentrations of the CCR5-specific small molecule inhibitor, AD101. By 19 passages, an escape mutant emerged with a >20,000-fold resistance to AD101. This virus was cross-resistant to a related inhibitor, SCH-C, and partially resistant to RANTES b...

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