objective: amphotericin b (amb) is an ancient antifungal drug and proper for treatment of systemic fungal infection. unfortunately, this antibiotic has shown some side effects such as nephrotoxicity. therefore, recently new amb formulated has been prepared for reduced toxicity and increased effectiveness. materials and methods: amb nanocapsules prepared from polymers such as poly d, l-lactide-...

The purpose of this article is to review the anatomical features of the most common nerve entrapment sites of the brachial plexus and major peripheral nerves of the upper limb. In this account, the term "entrapment" is considered to be caused by compression, tension, or friction, or any combination of these factors. The anatomy, including important relationships of the brachial plexus, is revie...

To prepare lomustine-iohexol compound liposomes, and evaluate the properties, determine the entrapment efficiency. Liposomes were prepared by reverse evaporation method; orthogonal design was used to optimize the formulation. Free drugs and liposomes were separated using protamine aggregation method and entrapment efficiency was determined by HPLC. The optimal formula was as follows: soybean ph...

BACKGROUND Prior research has validated the construct of a suicide crisis syndrome (SCS), a specific psychological state that precedes and may precipitate suicidal behavior. The feeling of entrapment is a central concept of the SCS as well as of several other recent models of suicide. However, its exact relationship with suicidality is not fully understood. In efforts to clarify the exact role ...

Anatomical variations of the flexor digitorum superficialis (FDS) muscle and tendon unit are frequently reported by anatomists and clinicians. Anatomical muscle variations of the FDS and its tendons may include variations of muscle belly, presence of accessory or duplicate tendons, abnormal tendon connections, and absence of muscle or tendon components. Such variations may or may not have clini...

A novel bio nanocomposite of Carboxymethyl Starch (CMS)-Chitosan (CS)-Montmorillonite (MMT) was developed for Curcumin delivery. To improve Curcumin entrapment into Cs-CMS-MMT, different ratios of Chitosan (Cs), Carboxymethyl Starch (CMS) and MMT were used. Particle size and Curcumin entrapment efficiency (EE) were highly affected by different formulation variables. Polysaccharide concentration...

The contractile and electrical properties of motor units in the first dorsal interosseous muscle of the hand have been studied in 26 patients with ulnar neuropathies and motor neurone disease (amyotrophic lateral sclerosis). Among patients with unilateral pressure or entrapment ulnar neuropathies, there was a tendency for the twitch tensions for single motor units to be smaller, while the surfa...

The purpose of this article is to provide information that facilitates the critical evaluation of the thoracic outlet syndrome and other nerve entrapment syndromes in the regions of the posterior cervical triangle and the shoulder. General comments regarding entrapment are followed by discussions of specific entrapment sites. Each discussion stresses the anatomic view and includes comments on c...

The pyriformis syndrome is a rare entrapment neuropathy in which the sciatic nerve is compromised by the pyriformis muscle or other local structures. It is an important cause of buttock pain that may often be accompanied by sciatica. The pain is usually increased by muscular contraction, palpation or prolonged sitting. The diagnosis relies on the clinical presentation and the electromyelography...

Cubital tunnel syndrome is one of the common upper extremity problem encountered. A mild syndrome can be often treated without surgery, but a failure of conservative treatment with constant symptoms or muscle atrophy and weakness requires surgical intervention. Despite the fact that is the second most common nerve entrapment in the upper limb, there is no accepted gold standard in the surgical ...