Exercise-induced muscle damage is a well-described consequence of strenuous exercise, but its potential importance in the evolution of animal activity patterns is unknown. We used plasma creatine kinase (CK) activity as an indicator of muscle damage to investigate whether the high intensity, long-duration flights of two migratory shorebird species cause muscle damage that must be repaired durin...

This study assessed ultrastructural muscle damage in young (20-30 yr old) vs. older (65-75 yr old) men after heavy-resistance strength training (HRST). Seven young and eight older subjects completed 9 wk of unilateral leg extension HRST. Five sets of 5-20 repetitions were performed 3 days/wk with variable resistance designed to subject the muscle to near-maximal loads during every repetition. B...

Alcoholic myopathies are characterized by neuromusculoskeletal symptoms such as compromised movement and weakness. Although these symptoms have been attributed to neurological damage, EtOH may also target skeletal muscle. EtOH exposure during zebrafish primary muscle development or adulthood results in smaller muscle fibers. However, the effects of EtOH exposure on skeletal muscle during the gr...

Inflammation and pain induced by delayed onset muscle soreness (DOMS) can be induced by eccentric exercise or an unaccustomed activity. The condition can causes problems in exercising and for athletes. The purpose of this study was to assess the effect of 150mg curcumin supplementation immediately after intensive eccentric exercise. Evaluations were made for total antioxidant Capacity (TAC), mu...

The aim of the present study was to investigate The effect of HMB-FA supplementation on the muscle damage markers after soccer matches. 24 male soccer players (age: 23±3 years, BMI: 22.8±2 kg/m2) were voluntarily selected as the statistical sample of this study and were divided into two Suppplement and Placebo groups (n=12). In this study, subjects participated in a weekly soccer microcycle wit...

PURPOSE Fourteen male cyclists were studied to compare the effect of carbohydrate-protein-antioxidant beverage (CHOPA) to an isocaloric carbohydrate-only (CHO) beverage on time to fatigue and muscle damage. METHODS Subjects performed two sets of rides to exhaustion on a cycle ergometer. In each set, the first ride was performed at 70% VO2peak, and the second was performed 24 h later at 80%. C...

Skeletal muscle is a dynamic tissue that responds adaptively to both the nature and intensity of muscle use. This phenotypic plasticity ensures that muscle structure is linked to patterns of muscle use throughout the lifetime of an animal. The cascade of events that result in muscle restructuring - for example, in response to resistance exercise training - is often thought to be initiated by mu...

Exercise involving lengthening contraction (LC) often results in delayed myofiber damage and functional deficits over the ensuing days. The present study examined whether the stretch speed of LC is a determinant of damage severity. Under isoflurane anesthesia, LC was repeatedly induced in rat ankle extensor muscles at different stretch speeds (angular velocities of 50, 100, 200, and 400 deg/sec...