Multivariate calibration methods (partial least squares calibration, back propagation multilayer perceptrons networks, radial basis functions and generalized regression neural networks) were applied to the simultaneous fluorometric quantification of levofloxacin, garenoxacin and grepafloxacin, without previous separation steps. A data matrix was obtained by registering the emission spectra of m...

Simultaneous spectrophotometric determination of salicylamide and paracetamol by H-point standard addition method (HPSAM) and partial least squares (PLS) calibration is described. The results showed that simultaneous determinations could be performed with the ratio 0.2:5–20:1 for salicylamide – paracetamol. A partial least – squares multivariate calibration method for the analysis of binary mix...

The robustness of a dual-beam, optical null, Fourier-transform near-infrared (FTNIR) spectrometer was investigated by means of online, near-infrared measurements and predictions of urea concentrations in spent dialysate during hemodialysis treatment. Simple multivariate calibration using a few factors based on a small number of prepared samples provided stable and accurate predictions over a pe...