BACKGROUND AND PURPOSE Poststroke fatigue is common and reduces quality of life. Current evidence for intervention is limited, and this is the first placebo-controlled trial to investigate treatment of poststroke fatigue with the wakefulness promoting drug modafinil. METHODS The trial was randomized, double-blinded, and placebo-controlled. Patients were treated with 400-mg modafinil or placeb...

BACKGROUND Dental malocclusions can be considered not only as an oral health problem, because they are linked to quality of life perception. Many factors related to malocclusion have strong influences on the perception of facial esthetics (eg, anterior tooth alignment, tooth shape and position, lip thickness, symmetric gingival or tooth contour, lip profile, and overjet). Many reports have show...

Objective To determine the effectiveness of screening for visual impairment in people aged 75 or over as part of a multidimensional screening programme. Design Cluster randomised trial. Setting General practices in the United Kingdom participating in the MRC trial of assessment and management of older people in the community. Participants 4340 people aged 75 years or over randomly sampled from ...

Background: The General Comfort Questionnaire (GCQ), developed by Katharine Kolcaba, has not been validated in any speaking Spanish country, subsequent validation is necessary. Objectives: To translate the General Comfort Questionnaire (GCQ) in English language into Spanish (S-GCQ) and to examine the psychometric properties of the S-GCQ. Method: Validation was performed on a randomly selected s...

The aim was to develop a multidimensional computerized adaptive short-form questionnaire, the MusiQoL-MCAT, from a fixed-length QoL questionnaire for multiple sclerosis.A total of 1992 patients were enrolled in this international cross-sectional study. The development of the MusiQoL-MCAT was based on the assessment of between-items MIRT model fit followed by real-data simulations. The MCAT algo...

OBJECTIVE To determine the effectiveness of screening for visual impairment in people aged 75 or over as part of a multidimensional screening programme. DESIGN Cluster randomised trial. SETTING General practices in the United Kingdom participating in the MRC trial of assessment and management of older people in the community. PARTICIPANTS 4340 people aged 75 years or over randomly sampled...

OBJECTIVE Research on driving behavior and personality traits is a key factor in the development of driver-oriented safety interventions. However, research is fragmented and a multidimensional perspective is lacking. The primary aim of this study is to assess the multiple relationships between driving styles and personality traits using the alternative 5-factor model. A secondary goal is to det...

INTRODUCTION Evaluating patient-reported outcomes is complex. These difficulties may explain weaknesses with some existing tools: mainly, they rely on expert instead of patient views or are not metrically sound. The purpose of this study was to develop and validate a multidimensional self-reported questionnaire, specifically assessing the satisfaction of patients undergoing regional anesthesia,...

BACKGROUND The aim of the current study is to determine the effects of caregiving on bereavement outcome. The study will address two important gaps in the research literature: (1) the relationship between pre-death distress and post-death outcomes and (2) family caregivers' anticipation and preparation of the death of the person for whom they care. METHODS/DESIGN We will conduct a longitudina...

The current study sought to investigate measurement discrepancies in self-report assessment of experiential avoidance (EA). Recent research indicates that EA may be more appropriately conceptualized as a multidimensional construct, operationally defined in terms of specific avoidance strategies. To test this notion, EA was measured using two self-report assessment instruments, the Acceptance an...