Shortcut methods are valuable tools in the early stages of chemical process design, where numerous flowsheet alternatives need to be evaluated to determine the most energy-efficient, feasible flowsheet. Various shortcut methods based on tray-to-tray calculation and pinch point analysis for the inspection of feasibility and the determination of the minimum energy demand (MED) for homogeneous non...

This work presents the results from dynamic modeling and control of an azeotropic distillation system. The model was validated with experimental data from a packed distillation unit. The physically-based process dynamic model, developed in HYSYS, was linked online with the control software used in the process. Model parameters were modified online using a feedback configuration to eliminate the...

We show that the minimum energy requirement for separation of a multicomponent mixture in a three-product Petlyuk arrangement is equal to the minimum energy for the most difficult of the two separations (top/middle or middle/bottom product) in a conventional single column. In the Vmin diagram (part 1 of this series), this is simply the highest peak. These results are based on an analytical solu...

We consider separation of ideal multicomponent mixtures with constant relative volatilities and constant molar flows and at constant pressure. The exact analytical solution of minimum energy in a generalized Petlyuk arrangement for separation of N-component feed into M products has been derived. Interestingly, the minimum-energy solution in a complex integrated Petlyuk arrangement is equal to t...

Distillation separates compounds by the variation in how effortlessly they vaporize. The two main types of standard distillation comprise unremitting distillation and batch distillation. Unremitting distillation, as the name says, unremittingly takes a feed and separates it into two or more products. Batch distillation takes on lot (or batch) at a time of feed and splits it into products by sel...

Three UV spectrophotometric methods have been developed, simultaneous equation method, multicomponent analysis (II) and derivative spectroscopy method (III). The absorption maxima of the drugs were found to be 247, 259 and 272 nm, respectively for efavirenz, tenofovir disoproxil fumarate and lamivudine in methanol:water (50:50) solvent system. Efavirenz, tenofovir disoproxil fumarate and lamivu...

An examination of the program of the next meeting of distillation and absorption indicates there are only a few lectures on thermodynamcis. The authors asked some important companies to give their view of the trends in thermodynamics. This plenary lecture concerns some of the remaining challenges in the thermodynamics related to distillation: data banks and locations for measuring experimental ...