The first enantioselective organocatalytic Mukaiyama-Michael reaction using alpha,beta-unsaturated aldehydes has been accomplished. The use of iminium catalysis has provided a new strategy for the enantioselective addition of 2-silyloxy furans to unsaturated aldehydes to generate a variety of butenolide systems, an important chiral synthon found among many natural isolates. The (2S,5S)-5-benzyl...

This present mini-review covers recently published results on Cu(I) and Cu(II) complexes immobilized on polystyrene carriers, which are used as heterogeneous, eco-friendly reusable catalysts applied for carbon-carbon and carbon-nitrogen forming reactions. Recent advances and trends in this area are demonstrated in the examples of oxidative homocoupling of terminal alkynes, the synthesis of prop...

A unified approach to ent-atisane diterpenes and related atisine and hetidine alkaloids has been developed from ent-kaurane (-)-steviol (1). The conversion of the ent-kaurane skeleton to the ent-atisane skeleton features a Mukaiyama peroxygenation with concomitant cleavage of the C13-C16 bond. Conversion to the atisine skeleton (9) features a C20-selective C-H activation using a Suárez modifica...

Vetiveröl wird im Multitonnen-Maßstab aus den Wurzeln des Vetivergrases gewonnen und ist einer der begehrtesten Duftbausteine modernen Parfümerie. Das exquisite ätherische Öl, das sich in über einem Drittel aller Parfüms findet, eine komplexe Mischung Hunderten von unterschiedlichen Verbindungen, wobei riechende Prinzip, für charakteristischen sanften süßen, transparenten, holzig-ambrierten Ger...