abdomen accompanied by mottling, bronchial rales back of both lungs, resonance not clear ; temperature normal 15th day ; 16 th day rash and mottling disappeared. Case 5.?Admitted 6th day of illness, rash present, purplish red ; 8th day rash darker, disappearing on pressure, cough ; 10th day very drowsy, sordes in teeth, cannot protrude tongue ; 11th passing watery motions in bed, prostration ma...

OBJECTIVE To determine the safety of lamotrigine rechallenge after a first episode of skin rash in bipolar patients. METHOD An open cases prospective study was conducted with patients who, developed a skin rash when first treated with lamotrigine, were refractory to other treatments, and were offered lamotrigine rechallenge using a different dose titration. Additionally a review was performed...

This study reports two adult-onset Still's disease (AOSD) cases that met both Yamaguchi's and Fautrel's criteria and that presented with notable clinical manifestations. One case presented with atypical dermographism-like rash with an extremely high ferritin level. The other case presented with typical salmon-pink maculopapular rash but had atypical positive rheumatoid factor. This suggests tha...

WY Lam, FRCPath, FHKAM(Pathology) Cytomegalovirus (CMV) is a DNA virus belonging to the herpesvirus family. They replicate in the nucleus and form intranuclear inclusions and lead to giant cell formation. They have the ability to cause latent infection in humans. Reactivation from latency might occur in immunocompromised patients. It causes encephalitis, pneumonitis, colitis, retinitis and also...

PURPOSE Data from two large phase III studies were analyzed to characterize the correlation between the occurrence of rash during treatment with the epidermal growth factor receptor inhibitor erlotinib and improved clinical outcomes. EXPERIMENTAL DESIGN Overall survival, progression-free survival (PFS), and tumor response were compared between patients in a rash-evaluable subset who did or di...

A 9-year-old girl presented with fever for 4 days. On day 8 of illness, when her fever subsided, she developed hypotension. Her platelet count dropped to 15000/ml and hematocrit increased to 42.8%. She was resuscitated with fluid boluses. She developed typical dengue rash of convalescence 3 days after defervescence (Fig. 2). Her dengue serology IgM and IgG were positive, suggestive of secondary...