In this review, we summarize the most important recent developments in the treatment of amyotrophic lateral sclerosis (ALS). In terms of disease-modifying treatment options, several drugs such as dexpramipexole, pioglitazone, lithium, and many others have been tested in large multicenter trials, albeit with disappointing results. Therefore, riluzole remains the only directly disease-modifying d...

Cognitive dysfunction is frequent in multiple sclerosis patients and has important and negative consequences for daily activities and quality of life of subjects. Disease modifying treatments for multiple sclerosis reduce the incidence of relapses and may prevent disease progression, but the influence on cognitive impairment is unclear, due to several limitations of the available studies. Moreo...

razi & mowlavi have both explained the fearing of death; although in different ways. razi looks death, in any way and for anybody, as a disease and a fictitious phenomenon; so, as physician tries to treat it rationally. neglecting the imagination of death is the best way to get out of fearing pressures; because thinking to death can unconsciously bring a great deal of fear. but mowlavi (rumi) e...

Age progression is the process of modifying a photograph of a person to represent the effect of aging on their appearance. I proposed to create an application that displays the entire age progression of people face throughout their life time. Given a portrait picture of an adult, the application shows how the person change from a baby face into an elder face. An interactive application with a s...

Two cases of inflammatory bowel disease, occurring in adolescence and complicated by anorexia nervosa, are presented. The management of the bowel disease with corticosteroids appeared to precipitate the eating disorder in one case whereas covert withdrawal of steroid treatment led to life threatening complications of inflammatory bowel disease in the other. The difficulties of managing two seri...