MAIN RESULTS After one year, prevalence of psychiatric illness significantly increased in people with moderate to severe and mild traumatic brain injury, compared with controls (moderate to severe: 49%; mild: 34%; control: 18%; see table 1, http://www.ebmentalhealth.com/ supplemental). People with prior psychiatric illness are more likely to suffer from a psychiatric illness after traumatic bra...

BACKGROUND Traumatic Brain Injury (TBI) is the leading cause of death in all age group. The incidence of CSI increases with the severity of TBI so prompt care of cervical spine is necessary in all patients with moderate to severe head injury. The objective of this study was to determine the frequency of cervical injury in patients with moderate to severe head injury and different types of traum...

BACKGROUND This study evaluates post-ICU outcomes of patients admitted with moderate and severe Traumatic Brain Injury (TBI) in a tertiary neurocritical care unit in an low middle income country and the performance of trauma scores: A Severity Characterization of Trauma, Trauma and Injury Severity Score, Injury Severity Score and Revised Trauma Score in this setting. METHODS Adult patients di...

The methodology for studies designed to investigate potential risk factors for sports injury is reviewed, using the case of hamstring strains as an example. Injuries result from a complex interaction of multiple risk factors and events. Therefore, a multivariate statistical approach should be used. In addition, the sample size of the study needs to be considered carefully. Sample size mainly de...

Despite the associated morbidity and mortality, underlying mechanisms leading to the development of acute lung injury (ALI) remain incompletely understood. Frequently, ALI develops in the hospital, coinciding with institution of various therapies, including the use of supplemental oxygen. Although pathological evidence of hyperoxia-induced ALI in humans has yet to be proven, animal studies invo...

STUDY DESIGN Experimental investigation of an acute thoracic spinal cord injury model in rats involving acute clip compression that simulates human injury. OBJECTIVE To assess the dose-response of this model for the relationship between the force of injury on the rat thoracic spinal cord and histological and functional outcome measures. SUMMARY OF BACKGROUND DATA Acute extradural clip compr...