a group of regioisomeric 5-oxo-1,4,5,6,7,8 hexahydroquinoline derivatives possessing a cox-2 so2me pharmacophore at the para position of the c-2 or c-4 phenyl ring, in conjunction with a c-4 or c-2 phenyl (4-h) or substituted-phenyl ring (4-f,4-cl,4-br,4-ome,4-me, 4-no2), were designed for evaluation as selective cyclooxygenase-2 (cox-2) inhibitors. these target 5-oxo-1,4,5,6,7,8 hexahydroquino...

this paper presents a comprehensive case study on electro-mechanical analysis of mems[1] variable capacitors. using the fundamental mechanical and electrical equations, static and dynamic behaviors of the device are studied. the analysis is done for three different modes, namely: dc (static mode), small signal ac and large signal regime. a complete set of equations defining dynamic behavior of ...

in this work, several machine learning techniques are presented for nanofiltration modeling. according to the results, specific errors are defined. the rejection due to nanofiltration increases with pressure but decreases with increasing the concentration of chloride ion. methods of machine learning represent the rejection of nanofiltration as a function of concentration, ph, pressure and also ...

information on the thermophysical properties of the iranian ultrafiltrated (uf) white cheese is very limited. in this research, those thermal properties determined experimentally were thermal conductivity, specific heat, density and water activity. the thermal conductivity and specific heat of iranian ultrafiltrated white cheese (iufwc) ranged from 0.447 to 0.480 w m-1 °c-1 and from 3.871 to 4....

groundwater is a major source of water for domestic, industrial, and agricultural sectors in many countries. the main objective of this research was to provide an overview of present groundwater quality using parameters such as calcium, magnesium, sodium, chloride, sulfate, ph, and electrical conductivity (ec) in the mehran plain, ilam province using gis and geostatistical techniques. a total o...

arsenic is one of the heavy metals and nearly all its compounds, especially organic compounds, are toxic. the wide spectrum of diseases caused by this element has led to evaluation of the toxicity of different arsenic species and identification of the major natural and anthropogenic pollution sources of it in the nature. mining activities are among the main sources of anthropogenic pollution of...

introduction: one of the types of hospital management information systems is decision support information system (dsis). this system uses decision-making models and databases for preparing specific information to support their semi-structured or unstructured decisions. the present study aimed to design a decision dsis model for board of trustees of ayatollah kashani hospital, shahrekord, iran. ...

Visual modeling languages are appealing because "a picture tells more than a thousand words." The UML is such a visual language and is well known for its graphical notation and diagramming techniques. However, pictures often only tell half of the story and additional information needs to be captured in a different way. For this reason the UML includes the Object Constraint Language (OCL), a tex...

Clinical pathways describe treatment processes within a hospital. They can be used as process models, which can be controlled by implemented workflow models in information systems. This enables (semi-) automated processes, and they are therefore high potential for an improved quality management and seamless IT support. Surprisingly, there are no published process models that describe the implem...

Process reuse (the ability to construct new processes by assembling already built ones) and process harvesting (the ability to build generic processes that may be further reused, from existing ones) are two crucial issues in process technology. Both activities involve defining a set of mechanisms, like abstraction, adaptation, composition, etc. which are appropriate to achieve their goals. In t...