The poorly water soluble antidiabetic drug gliclazide was selected to study the effect of excipients on dissolution rate enhancement. Ordered mixtures of micronized gliclazide with lactose, mannitol, sorbitol, maltitol and sodium chloride were prepared by manual shaking of glass vials containing the drug and excipient(s). Different water soluble excipients, addition of surfactant and superdisin...

The parameterization of unresolved processes in oceanographic models is complicated by the interplay of processes on a wide variety of space and time scales. The lack of spectral gaps further complicates the situation, though perhaps not as seriously as might be feared. Understanding the interaction of different processes, and determining which one is critical, or rate-controlling, may be aided...

We introduce the notion of conductance in discrete dynamical systems defined by iterated maps of the interval. Our starting point is the notion of conductance in the graph theory. We pretend to apply the known results in this new context.

The p-shuffle is a natural generalization of the dovetail shuffle. It is defined as follows. First, the deck is cut into a top stack and a bottom stack so that the distribution of the size of the top stack is Binomial (N, p), where N is the total number of cards in the deck. Then, conditional on the outcome of the cut, the two stacks are “riffled” in such a way that all possible riffles (interl...

In order to define an appropriate mathematical model for the flow and mixing characteristics of a high-rate algae pond, impulse-response tests were carried out on an experimental pond located at Ein Karem, near Jerusalem, at Reynolds number = 10 5, and on two scale models of the same pond, at 2 000 < Re < 20 000. Each pond consisted of a continuous rectangular channel with seven 180° bends, and...

The performance of micro-mixers is evaluated in terms of deviations from perfectly mixed state and mixing length (i.e., device length required to achieve perfect mixing). Different variations of T-mixer are reported for improved mixing performance, including geometric constrictions/obstacles embedded in the channel wall, heterogeneously charged walls, grooves on channel base, etc. Most of the r...