نتایج جستجو برای: mirna and multiple sclerosis
تعداد نتایج: 16931715 فیلتر نتایج به سال:
neuroinflammation has a significant role in induce of multiple sclerosis (ms) many approaches have been used to treat ms, but none of these methods have not been able to fully improve. one of the methods can suppress inflammation and regenerate the nervous system is the use of cell therapy. using cell therapy in pre-clinic phase can be realized, it's mechanism and potency to suppress neuro...
background: vitamin b12 (cobalamin) deficiency can result in some clinical and paraclinical characteristics similar to what is seen in multiple sclerosis (ms) patients. this study aimed to evaluate the controversial association between vitamin b12 deficiency and ms. methods: we measured serum vitamin b12 in 60 patients with ms and 38 healthy controls. clinical disability was evaluated according...
background: the association between the prevalence of multiple sclerosis (ms) and latitude gradient indicates the importance of environmental factors in ms susceptibility. sunlight’s ultraviolet radiation, its ability to influence melatonin, and an imbalance of melatonin in the central nervous system (cns) may be involved in this process. methods: this case‑control study was conducted in isfaha...
background: management of multiple sclerosis (ms) is based on the usage of immunosuppressive and immune-modulating medications. cytokines play an important role in the pathogenesis of ms. objective: to evaluate the effects of rapamycin on the concentrations of th1/th2/th17 serum cytokines in patients with ms. methods: six patients with relapsing remitting ms as a case group and 6 healthy indivi...
multiple sclerosis (ms) is the most prevalent disease caused by the inflammatory demyelinating process that causes progressive nervous system degeneration over the time. optical coherence tomography (oct) is a non-invasive optical imaging technology, which can measure the thickness of retinal nerve fiber layer as well as the diameter of the macula. the purpose of the study is evaluation oct fin...
Background & Aim: Restless legs syndrome (RLS) is a sensorimotor disorder that is frequently observed in patients with multiple sclerosis. This study aimed to determine the effect of stretching exercises on the severity of restless legs syndrome symptoms in patients with multiple sclerosis. Methods & Materials: This quasi-experimental study with control group (IRCT2016041627427N1) was conduc...
Background & Aim: Patients with multiple sclerosis suffer from permanent pain. It is being increased to apply relaxation therapy to decrease patients' pain. The progressive muscle relaxation make the muscles feel more relaxed. The aim of this study was to assess the effect of progressive muscle relaxation on pain among patients with multiple sclerosis . Methods & Materials: A randomized ...
Background: Multiple sclerosis is a progressive disease of the central nervous system, that for a reason a variety of symptoms can cause destructive effects on quality of life. The aim of this study was to determine the effect of applying Orem’s self-care model on mental aspect of quality of life in patients with multiple sclerosis . Methods: In this quasi-experimental study, 74 patients wi...
Background: Multiple sclerosis is the most common demyelinating disease of central nervous system. We prepared this study to find its epidemiologic pattern in the Iranian society.Methods: This case-series study involved 70 patients diagnosed with multiple sclerosis according to the McDonald criteria and admitted to the Iranian Center of Neurological Research at Imam Khomeini Hospital from 2002 ...
Introduction: The purpose of this study was to examine the effects of water exercises on the quality of life in patients with multiple sclerosis. Methods: 30 multiple sclerosis patients (40-65 years old) were selected by available sample. They were divided into control and experimental groups. The instrument was the Quality of Life Questionnaire (SF-36) in this study. The experi...
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