STUDY OBJECTIVE To assess the efficacy of botulinum toxin type A in lowering the frequency of migraine headaches in patients with episodic migraines. DESIGN Meta-analysis of eight randomized, double-blind, placebo-controlled trials. PATIENTS A total of 1601 patients with a history of episodic migraine headaches classified as those experiencing headaches fewer than 15 times/month over a 3-mo...

The theory that smoking could be implicated in the pathogenesis of migraine has been investigated in a prospective survey by the use of a questionnaire and the measurement of carboxyhaemoglobin (COHb) levels in patients attending a migraine clinic. There was a low incidence of smokers in patients attending for routine consultations and only a small percentage of patients thought that smoking wa...

AIMS The medium term prognosis of cyclical vomiting syndrome (CVS) was studied to determine the proportion of affected individuals who had gone on to develop headaches fulfilling the International Headache Society criteria for migraine. METHODS Twenty six (76%) of 34 CVS sufferers identified from the authors' clinical records were traced, and all agreed to participate. Each child was matched ...

Background: The prevalence of migraine headaches significantly increased in girls after menarche. This indicated that there is a closely relation between hormonal changes especially the estrogen level with migraine headaches. Objectives: The aim of this work was to determine the frequency of migraine and its associated factors in medical students affected with premenstrual syndrome (PMS). ...

A questionnaire survey was conducted to clarify the headache situation in people with chronic during new coronavirus disease 2019 (COVID-19) infection. on internet. The subjects were 600 women their 20s 40s who infected 7th wave of COVID-19 infection from July October 2022. Subjects (55.7%) had headaches at time infection, and most recuperating home. Other (excluding migraine) accounted for abo...

BACKGROUND Migraine is a highly prevalent and disabling illness that remains substantially undiagnosed in primary care. Because of the potential value of a screening tool, the current study was designed to establish the validity and reliability of a brief, self-administered migraine screener in patients with headache complaints in the primary care setting. METHODS A total of 563 patients pres...

Recent studies on Multiple Sclerosis (MS) pathology mention the involvement of "tertiary B cell follicles" in MS pathogenesis. This inflammatory process, which occurs with interindividually great variance, might be a link between MS pathology and headaches. The aim of this study was to detect the prevalence of headaches and of subtypes of headaches (migraine, cluster, tension-type headache [TTH...

An interest in pursuing new theories of the underlying etiology of migraine headaches has been sparked by previously published reports of an association between amelioration of migraine headache symptoms and corrugator resection during endoscopic brow lift. This theory has further been reinforced by recent publications documenting improvement in migraine headaches following injection of botulin...

Behavioral interventions, particularly biofeedback and relaxation therapy, have demonstrated their effectiveness in the treatment of both adults and older children with migraine in controlled trials. The physiological basis for their effectiveness is unclear, but data from one trial suggest that levels of plasma beta-endorphin can be altered by relaxation and biofeedback therapies. The data sup...