Migraine is a primary headache disorder that is characterized by severe headaches and impairment of autonomic nervous system function. This neurovascular disorder ranks as the eighth cause of disability in the world. Migraine is basically an inflammation problem caused by activation of the trigeminal neurovascular complex. Neuropeptides like serotonin, calcitonin gene-related peptide (CGRP) and...

Migraine is a neurovascular disorder that is characterized by unilateral, pulsatile headaches. Migraine due to its individual and social effects is known as a major cause of disability in the world. The main complication of this disease is chronification that is known as chronic migraine (CM). It seems that several factors contribute to migraine chronification such as age, female gender, obesit...

BACKGROUND To estimate utility values for different levels of migraine pain severity from a United Kingdom (UK) sample of migraineurs. METHODS One hundred and six migraineurs completed the EQ-5D to evaluate their health status for mild, moderate and severe levels of migraine pain severity for a recent migraine attack, and for current health defined as health status within seven days post-migr...

Migraine is a common neurological disorder causing huge suffering both for the individuals affected and for society. As migraine is a chronic disorder that cannot be cured, but merely relieved, prevention is of great importance. Exercise is often recommended in migraine prevention, but evidence of efficacy is still lacking. It can be difficult for patients with migraine to perform exercise, sin...

INTRODUCTION Migraine has a considerable social, economic, physical and emotional burden but remains underdiagnosed and undertreated. A specific migraine screening tool could help remove barriers to health care and be an attractive instrument for epidemiological studies. The objective of this work was to assess the validity of an extended French version of ID Migraine™ as a migraine-screening t...

..................................................................................................................... 9 REVIEW OF THE LITERATURE .............................................................................. 10 1. CLINICAL CHARACTERISTICS OF MIGRAINE AND EPISODIC ATAXIA TYPE 2 ........................... 10 1.1. Migraine with and without aura .......................................

The effect of acute migraine attack and rectally given metoclopramide on the absorption of orally given tolfenamic acid (300 mg) was investigated in seven female patients in a crossover study consisting of four phases, two without migraine and two during migraine. Metoclopramide hydrochloride (20 mg) or placebo was given double-blind. Migraine attacks delayed the absorption of tolfenamic acid. ...

OBJECTIVES/HYPOTHESIS To better understand the features of migraine in Meniere's disease (MD). STUDY DESIGN Retrospective review of prospectively obtained surveys in an outpatient clinic of a tertiary medical center. METHODS Detailed questionnaires on headaches and dizziness were given to consecutive patients presenting with dizziness. The responses were verified by the clinician with the p...

BACKGROUND No study has investigated the impacts of migraine on depression, anxiety, and somatic symptoms and remission at the two-year follow-up point among patients with major depressive disorder (MDD). This study aimed to investigate the above issues. METHODS Psychiatric outpatients with MDD recruited at baseline were investigated at a two-year follow-up (N = 106). The Hamilton Depression ...