OBJECTIVES there are indications that patients with a mitochondrial disorder (MID) develop malignomas or benign tumors more frequently than the general population. The aims of the study were to find out if the prevalence of tumors is actually increased in MID-patients and which of the malignomas or benign tumors are the most frequent. METHODS The charts of MID-patients were retrospectively ev...

The prevalence of the Moraxella catarrhalis immunoglobulin D (IgD)-binding outer membrane protein MID and its gene was determined in 91 clinical isolates and in 7 culture collection strains. Eighty-four percent of the clinical Moraxella strains expressed MID-dependent IgD binding. The mid gene was detected in all strains as revealed by homology of the signal peptide sequence and a conserved are...

We discuss the instrumental factors which constrain the sensitivity limits of the mid-infrared camera (ISOCAM) of ESA's Infrared Space Observatory (ISO). The observing strategy judged to be best suited to faint-source detection is described. A data analysis technique adapted to the extraction of the faintest point-sources is discussed. We report the application of these techniques to an extreme...

Professional liability insurance crises in medicine have been intermittent, reaching magnitudes sucient to generate widespread concern only in the mid-1970s, the mid-1980s, and 2002-2003. It is easy for health policymakers and the public to view each crisis as an upswing of the same pendulum. Malpractice premiums rise, doctors accuse lawyers, lawyers point back at doctors, and legislatures deb...

GENERAL COMMENTARY article Front. Mar. Sci., 12 October 2022Sec. Deep-Sea Environments and Ecology Volume 9 - 2022 | https://doi.org/10.3389/fmars.2022.1045655

Diploid cells of Chlamydomonas reinhardtii that are heterozygous at the mating-type locus (mt+/mt-) differentiate as minus gametes, a phenomenon known as minus dominance. We report the cloning and characterization of a gene that is necessary and sufficient to exert this minus dominance over the plus differentiation program. The gene, called mid, is located in the rearranged (R) domain of the mt...