نتایج جستجو برای: microscale
تعداد نتایج: 5714 فیلتر نتایج به سال:
BACKGROUND CONTEXT Needle puncture of the intervertebral disc (IVD) is required for delivery of therapeutic agents to the nucleus pulposus and for some diagnostic procedures. Needle puncture has also been implicated as an initiator of disc degeneration. It is hypothesized that needle puncture may initiate IVD degeneration by altering microscale mechanical behavior in the annulus fibrosus (AF). ...
Efficient control of the self-renewal and pluripotency maintenance of embryonic stem cell (ESC) is a prerequisite for translating stem cell technologies to clinical applications. Surface topography is one of the most important factors that regulates cell behaviors. In the present study, micro/nano topographical structures composed of a gold nanoparticle layer (GNPL) with nano-, sub-micro-, and ...
A thorough investigation of the design considerations for microscale thermal field-flow fractionation and characterization of a 25 μm thin microscale thermal field-flow fractionation system is reported. A 4-50 times volume reduction from mesoscale and macroscale systems warrants customized design and operational conditions for microscale separation systems. Theoretical calculations are done to ...
One of the key goals of macromolecular modeling is to elucidate how macroscale physical properties arise from the microscale behavior of the polymer constituents. For many biological and industrial applications, a direct simulation approach is impractical due to to the wide range of length scales that must be spanned by the model, necessitating physically sound and practically relevant procedur...
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