Cardiovascular diseases (CVDs) are considered the most prevalent noncommunicable disease and leading cause of death worldwide. A plethora evidence has revealed that microRNAs (miRNAs) could control inhibition or progression CVDs by regulating pivotal cell processes ranging from metabolism homeostasis to programmed (PCD). Pyroptosis ferroptosis two major types nonapoptotic PCDs involved in patho...

Abstract Sticky platelet syndrome (SPS) is a disorder with familial occurrence and autosomal dominant trait characterized by hyperaggregability in response to low concentration of adenosine diphosphate (ADP) and/or epinephrine (EPI). The etiology SPS may be associated microRNAs (miRNAs), which are considered as potential biomarkers function antiplatelet therapy. We were monitoring the expressio...

MicroRNAs (miRNAs) are small non-coding RNA species involved in diverse physiological processes, including immunity. Accumulating evidence suggests that miRNA-induced gene silencing plays a significant role the regulation of intestinal immune system by gut commensal microbiota. This review aims to provide an overview miRNA-mediated crosstalk between microbiota and host system. First, we describ...

Skeletal muscle is a vital tissue not only for maintaining posture and body movements but also energy metabolism in human body. highly plastic response to various stimuli, resistance exercise or anabolic hormones can increase mass, which termed “muscle hypertrophy”. Contrary, immobility, aging severe illness reduce atrophy”. Loss of skeletal mass associated with loss independent living, the mor...

MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression at the post-transcriptional level. Current studies have shown that miRNAs are also present in extracellular spaces, packaged into various membrane-bound vesicles, or associated with RNA-binding proteins. Circulating miRNAs are highly stable and can act as intercellular messengers to affect many physiological processes. Mi...

Abstract Bladder cancer (BC), a urologic disease, commonly occurs globally and is very invasive. Patients with invasive BC have low 5-year survival rate. Hence, the mechanisms underlying development progression should be elucidated. MicroRNAs (miRNAs), as common noncoding RNAs, are receiving increasing attention because of their biological functions. The irregular expression patterns miRNAs lin...

MicroRNAs (miRNAs) constitute a potent layer of gene regulation by guiding RISC to target sites located on mRNAs and, consequently, by modulating their translational repression. Changes in miRNA expression have been shown to be involved in the development of all major complex diseases. Furthermore, recent findings showed that miRNAs can be secreted to the extracellular environment and enter the...

Expression of microRNAs changes markedly in tumours and evidence indicates that they are causatively related to tumourigenesis, behaving as tumour suppressor microRNAs or onco microRNAs; in some cases they can behave as both depending on the type of cancer. Some tumour suppressor microRNAs appear to be an integral part of the p53 and Retinoblastoma (RB) network, the main regulatory pathways con...

MicroRNAs or miRNAs are a form of small non-coding RNAs (ncRNAs) of 19-22 nucleotides in length in their mature form. miRNAs are transcribed in the nucleus of all cells from large precursors, many of which have several kilobases in length. Originally identified as intracellular modulators of protein synthesis via posttranscriptional gene silencing, more recently it has been found that miRNAs ca...