Engineered bacteria have great potential for medical and environmental applications. Fulfilling this potential requires controllability over engineered behaviors and scalability of the engineered systems. Here, we present a platform technology, microbial swarmbot, which employs spatial arrangement to control the growth dynamics of engineered bacteria. As a proof of principle, we demonstrated a ...

The overall composition of the mammalian intestinal microbiota varies between individuals: within each individual there are differences along the length of the intestinal tract related to host nutrition, intestinal motility and secretions. Mucus is a highly regenerative protective lubricant glycoprotein sheet secreted by host intestinal goblet cells; the inner mucus layer is nearly sterile. Her...

objective(s) studies have shown that morphine, in addition to its analgesic properties, has several effects on cell proliferation and apoptosis. there is also evidence that opioid receptors are present on chondrocytes. our main objective in the present study was to investigate the effects of morphine on rat femur growth cartilage. materials and methods this research was carried out on 18 4-week...

BACKGROUND Maternal atopic background and stimulation of the adaptive immune system with allergen interact in the development of allergic disease. Stimulation of the innate immune system through microbial exposure, such as activation of the innate Toll-like-receptor 2 (TLR2), may reduce the development of allergy in childhood. However, little is known about the immunological effects of microbia...

background: in the field of cellular therapy, the impact of confluence degree on harvesting or differentiation of bmmscs and the effect of cell-to-cell contact remain controversial. therefore, the effect of confluence on properties of bmmscs was studied and efficiency of confluence-associated osteogenic differentiation was identified. materials and methods: the impact of 20, 50, 70, 80 and 100%...

objective(s):degradation of sphingosine 1-phosphate (s1p), as a bioactive lipid, or deregulation of its production involves in tumor progression, metastasis and chemoresistance. since the tumor progression effects of s1p and its mechanism in chronic lymphoblastic leukemia and non-small cell lung cancer is not fully understood, we investigated the role and one of the mechanisms of s1p in tumor p...

background: a growing body of preclinical data indicates that statins may possess antineoplastic properties however, some studies have raised the possibility that statins may also have carcinogenic potential. methods: an air pouch model was used for angiogenesis. single or multiple applications of croton oil on the back of swiss albino mice with or without initiation by dimethylbenz(a)antherace...

abstract in this research, the effects of ba with different concentrations (0, 0.5, 1, 1.5, 2, 2.5 and 3 mg/l) in combination with iba (0, 0.01 and 0.1 mg/l) on bud growth and shoot proliferation and tdz with different concentrations (0, 1, 2, 3 and 4 mg/l) in combination with 0 and 0.5 mg/l iba on somatic embryogenesis from different parts of immature cotyledons (proximal, median and distal) w...

background: trichophyton verrucosum is a zoophilic fungus with a worldwide distribution. our aim was to investigate the proliferative effect of antigenic compounds of t. verrucosum on dermis fibro blasts and endothelial cells. methods: t. verrucosum was cultured in scc medium and was then transferred to a broth medium. surface antigens of this fungus were separated using the freeze and thaw met...

Recent evidence suggests that certain periodontal pathogens preferentially stimulate T cells expressing specific variable regions on the beta chain (Vbeta) of the T-cell receptor, which may indicate the presence of a superantigen. Superantigens are microbial proteins that activate large numbers of CD4(+) T cells in a Vbeta-specific manner. The purpose of this study was to determine whether Prev...